SDS-Page
Livin/BIRC7 Active Protein | BIRC7 active protein
Human Livin/BIRC7
Purity
>85% as determined by SDS-PAGE
Synonyms
Livin/BIRC7; Human Livin/BIRC7; KIAP; LIVIN; ML-IAP; RNF50; MLIAP; BIRC7 active protein
Host
E Coli
Specificity
An apoptosis inhibitor protein
Purity/Purification
>85% as determined by SDS-PAGE
Form/Format
Liquid
Source
Human
Biological Activity
Human Livin/BIRC7 reversibly inhibits DEVD-AFC cleavage activity in cell extracts activated by the addition of cytochrome c and dATP. The IC50 for this effect is typically 0.6-3.0uM.
Peptide Sequence
A DNA sequence encoding the human Livin/BIRC7 (AAH14475.1) (Met1-Ser298) is expressed with a polyhistide tag at the C-terminus.
Preparation and Storage
Store at -20 degree C
Centrifuge the vial prior to opening.
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA
Centrifuge the vial prior to opening.
Shipping: Gel Pack
Shelf Life: Est.~12 months
Country of Origin: USA
SDS-Page
SDS-Page
Related Product Information for BIRC7 active protein
Livin/BIRC7 is a member of the inhibitor of apoptosis protein (IAP) family. Its inhibits apoptosis through the inhibition of CASP3, CASP7, CASP9 and shows E3 ubiquitin-protein ligase activity. It promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway. It is expressed in fetal tissues and most solid tumors in humans. Livin/BIRC7 expression is a novel prognostic marker in adult acute leukemia. It might be involved in adrenocortical tumorigenesis and represents a new molecular marker of malignancy.
Product Categories/Family for BIRC7 active protein
NCBI and Uniprot Product Information
Protein Family
Similar Products
Product Notes
The BIRC7 (Catalog #AAA8400697) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Livin/BIRC7, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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