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Hepatocellular Carcinoma Active Protein

Hepatocellular Carcinoma, Human (Hemofiltrate Carcinoma Chemokine, HCC-1)

Purity
Molecular Biology Grade
99% by SDS-PAGE and HPLC analyses.
Synonyms
Hepatocellular Carcinoma; Human (Hemofiltrate Carcinoma Chemokine; HCC-1); Hepatocellular Carcinoma active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Molecular Biology Grade
99% by SDS-PAGE and HPLC analyses.
Form/Format
The sterile filtered solution was lyophilized without additives.
Stability The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 degree C. Reconstituted HCC-1 should be stored in working aliquots at -20 degree C.
Sequence
TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN
Biological Activity
Determined by its ability to chemoattract human monocytes using a concentration range of 5-20ng/ml.
Endotoxin Level
0.1ng/ug (1EU/ug).
Reconstitution
We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 degree C for 1 week or- 20 degree C for future use.
Preparation and Storage
-20 degree C
Related Product Information for Hepatocellular Carcinoma active protein
Human Hemofiltrate CC chemokine-1 (HCC-1) was first isolated from the hemofiltrate of patients with chronic renal failure. HCC-1 has a 46% amino acid sequence identity with MIP-1a/MIP-1b and 29-37% homology with other CC chemokines. Human HCC-1 is an 8.4kD protein containing 72 amino acid residues.
Product Categories/Family for Hepatocellular Carcinoma active protein

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
8.4kD
NCBI Official Full Name
hepatocellular carcinoma susceptibility protein

Uniprot Description

YY1AP1: Enhances transcription activation by YY1. May play a role in cell cycle regulation. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; regulation of cell cycle

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Product Notes

The Hepatocellular Carcinoma (Catalog #AAA635183) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: TESSSRGPYH PSECCFTYTT YKIPRQRIMD YYETNSQCSK PGIVFITKRG HSVCTNPSDK WVQDYIKDMK EN. It is sometimes possible for the material contained within the vial of "Hepatocellular Carcinoma, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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