Galectin-4 Active Protein | LGALS4 active protein

Galectin-4, 1-323aa, Human, His tag, E Coli (Bioactivity Validated)

Cat. Num. AAA203426

• Gene Names: LGALS4; GAL4; L36LBP
• Applications: SDS-Page
• Purity: > 95% by SDS-PAGE
• Synonyms: Galectin-4; 1-323aa; Human; His tag; E Coli (Bioactivity Validated); LGALS4; GAL4; L36LBP; Lactose-binding lectin 4; Antigen NY CO 27; Antigen NYCO27; GAL 4; Galectin 4; Galectin4; Lectin galactoside binding soluble 4; Homo sapiens galectin4 mRNA complete cds; L 36 lactose binding protein; L36 lactose binding protein; Lactose binding lectin 4; ; LGALS4 active protein

• Host: E Coli
• Purity/Purification: > 95% by SDS-PAGE
• Form/Format: Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol, 1mM DTT.
• Concentration: 1 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI
• Sequence Length: 323

• Applicable Applications for LGALS4 active protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Biological Activity: The ED50 for this effect is is equal or less than 2 ug/ml. Measured by its ability to ability to agglutinate human red blood cells.
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for LGALS4 active protein

Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic reactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. Recombinant Galectin-4 protein was expressed in E Coli and purified by using conventional chromatography techniques.

Product Categories/Family for LGALS4 active protein

Adhesion & Movement

References

Huflejt ME., et al. (1997) J Biol Chem. 272 (22):14294-303. ; Huflejt ME., et al. (2004) Glycoconj J. 20 (4):247-55.;

NCBI and Uniprot Product Information

• NCBI GI #: 5453712
• NCBI GeneID: 3960
• NCBI Accession #: NP_006140
• NCBI GenBank Nucleotide #: NM_006149.3
• UniProt Accession #: P56470
• Molecular Weight: 38.1 kDa (343aa), confirmed by MALDI-TOF.
• NCBI Official Full Name: galectin-4
• NCBI Official Synonym Full Names: galectin 4
• NCBI Official Symbol: LGALS4
• NCBI Official Synonym Symbols: GAL4; L36LBP
• NCBI Protein Information: galectin-4
• UniProt Protein Name: Galectin-4
• Protein Family: Galectin
• UniProt Gene Name: LGALS4
• UniProt Synonym Gene Names: Gal-4; L36LBP

NCBI Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. [provided by RefSeq, Jul 2008]

Uniprot Description

Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.