FGF basic active protein
FGF basic, FGF2 Protein (Active)
Applications
SDS-Page
Synonyms
FGF basic; FGF2 Protein (Active); FGF basic / FGF2 Protein (Active); FGF basic active protein
Host
E Coli
Form/Format
Lyophilized
Applicable Applications for FGF basic active protein
HPLC, SDS-PAGE
Biological Activity
The ED50, calculated by the dose-dependant proliferation of murine BALB/c 3T3 cells is < 2 ng/ml corresponding to a specific activity of 1.7 × 106 IU/mg.
Dimers
< 1% by SDS-PAGE
Endotoxin Level
< 0.1 ng/ug (1 EU/ug) by LAL test
Maximal Absorption Wave
277 ± 3 nm
Reconstitution
Reconstitute with sterile 18MΩ-cm H2O.
Storage Buffer
Each vial contains 10 mM Phosphate buffer and 200 mM NaCl (pH7.0) without preservatives.
Storage Buffer
Each vial contains 10 mM Phosphate buffer and 200 mM NaCl (pH7.0) without preservatives.
Preparation and Storage
Ship at 4 degree C. Upon receipt, store at -20 degree C or -80 degree C for long term. After reconstituting, it can store at 4 degree C for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze and thaw cycles.
Related Product Information for FGF basic active protein
Recombinant human basic FGF / FGF2 protein with molecular weight 18 kDa.
Fibroblast growth factor, basic (FGFB) also know as Fibroblast growth factor 2 (FGF2) is a wide-spectrum mitogenic, angiogenic, and neurotrophic factor that is expressed at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary. FGF-2 participates in controlling fates, migration and differentiation of neuronal cells, whereas it is not essential for their proliferation. FGF-2 accelerates fracture healing and prevents nonunion in primates, and therefore propose that it is a potent bone anabolic agent for clinical use. It could also be used in vivo to facilitate the mobilization and differentiation of resident cardiac precursors in the treatment of cardiac diseases
Fibroblast growth factor, basic (FGFB) also know as Fibroblast growth factor 2 (FGF2) is a wide-spectrum mitogenic, angiogenic, and neurotrophic factor that is expressed at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary. FGF-2 participates in controlling fates, migration and differentiation of neuronal cells, whereas it is not essential for their proliferation. FGF-2 accelerates fracture healing and prevents nonunion in primates, and therefore propose that it is a potent bone anabolic agent for clinical use. It could also be used in vivo to facilitate the mobilization and differentiation of resident cardiac precursors in the treatment of cardiac diseases
References
1. Dono, R., Texido, G., Dussel, R., Ehmke, H., Zeller, R. Impaired cerebral cortex development and blood pressure regulation in FGF2-deficient mice. EMBO J. 17: 4213-4225, 1998. 2. Kawaguchi, H., Nakamura, K., Tabata, Y., Ikada, Y., Aoyama, I., Anzai, J., Nakamura, T., Hiyama, Y., Tamura, M. Acceleration of fracture healing in nonhuman primates by fibroblast growth factor-2. J. Clin. Endocr. Metab. 86: 875-880, 2001. 3. Rosenblatt-Velin, N., Lepore, M. G., Cartoni, C., Beermann, F., Pedrazzini, T. FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes. J. Clin. Invest. 115: 1724-1733, 2005.
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Product Notes
The FGF basic (Catalog #AAA355638) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FGF basic can be used in a range of immunoassay formats including, but not limited to, HPLC, SDS-PAGE. Researchers should empirically determine the suitability of the FGF basic for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FGF basic, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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