BD3 Active Protein | Defb3 active protein
BD3, Recombinant, Human (beta Defensin-3)
Gene Names
Defb3; BD-3; MGC129397
Purity
Highly Purified98% (SDS PAGE and HPLC).
Synonyms
BD3; Recombinant; Human (beta Defensin-3); Defb3 active protein
Host
E Coli
Purity/Purification
Highly Purified
98% (SDS PAGE and HPLC).
98% (SDS PAGE and HPLC).
Form/Format
Supplied as a lyophilized powder. Reconstitute with 200ul dH20.
Application Notes
Suitable for use in Functional Assays.
Biological Activity
Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli.
Endotoxin Level
1EU/ug
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Defb3 active protein
Defensin beta 3 (BD-3) is a cationic non-haemolytic antimicrobial peptide and member of the beta-defensin family, highly expressed by skin and tonsils, which plays an important role in the innate immune response to potentially pathogenic microbes, including multiresistant S. aureus and vancomycin-resistant E. faecium.
Product Categories/Family for Defb3 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
5.1kD (45 amino acid residues)
NCBI Official Full Name
beta-defensin 3
NCBI Official Synonym Full Names
defensin beta 3
NCBI Official Symbol
Defb3
NCBI Official Synonym Symbols
BD-3; MGC129397
NCBI Protein Information
beta-defensin 3; OTTMUSP00000022575
UniProt Protein Name
Beta-defensin 3
Protein Family
UniProt Gene Name
Defb3
UniProt Synonym Gene Names
Bd3
UniProt Entry Name
DEFB3_MOUSE
Uniprot Description
Function: Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa. Ref.1
Subcellular location: Secreted.
Tissue specificity: Highest expression in salivary glands, epididymis, ovary and pancreas and to a lesser extent in lung, liver and brain. Low or no expression in skeletal muscle and tongue. Ref.1 Ref.3
Induction: By bacterial infection. Ref.1
Sequence similarities: Belongs to the beta-defensin family. LAP/TAP subfamily.
Research Articles on Defb3
Similar Products
Product Notes
The Defb3 defb3 (Catalog #AAA650863) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Suitable for use in Functional Assays. Researchers should empirically determine the suitability of the Defb3 defb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BD3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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