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4-1 BB Receptor Active Protein

4-1 BB Receptor, Recombinant, Human (4-1-BBR)

Purity
Highly Purified
98% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Synonyms
4-1 BB Receptor; Recombinant; Human (4-1-BBR); 4-1 BB Receptor active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Highly Purified
98% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Form/Format
Supplied as a lyophilized powder without additives.
Sequence
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Glu-Arg-Thr-Arg.
Biological Activity
Recombinant 4-1BBr is fully biologically active when compared to standard. The activity was determined by the inhibition of 4-1BB ligand mediated stimulation of IL-8 production by human PBMC. Results: 90% inibition using 1µg for both human 4-1BB ligand and human 4-1BB receptor.
Dimers and Aggregates
1% as determined by silver-stained SDS-PAGE gel analysis.
Endotoxin Level
0.1ng/ug (IEU/ug) of recombinant 4-1BBr.
Solubility
It is recommended to reconstitute the lyophilized human 4-1BB Receptor in sterile 18M -cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Preparation and Storage
-20 degree C
Stability: Lyophilized recombinant human 4-1BB Receptor although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution human 1-4BB Receptor should be stored at 4 degree C between 2-7 days and for future use below -180C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Related Product Information for 4-1 BB Receptor active protein
Recombinant Human soluble 4-1BB Receptor also called Tumor necrosis factor receptor superfamily member 9 produced in E. coli is a single, non-glycosylated polypeptide chain containing 167 amino acids, having a molecular mass of 17.718kD and containing the cysteine rich TNFR-like extracellular domain of recombinant 4-1BB Receptor. The human 4-1BB Receptor is purified by proprietary chromatographic techniques.
Product Categories/Family for 4-1 BB Receptor active protein

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Product Notes

The 4-1 BB Receptor (Catalog #AAA650496) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Glu-Ar g-Thr-Arg. It is sometimes possible for the material contained within the vial of "4-1 BB Receptor, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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