Mouse dual-specificity tyrosine- (Y) -phosphorylation regulated kinase 1B ELISA Kit | DYRK1B elisa kit
Mouse Dual specificity tyrosine-phosphorylation-regulated kinase 1B, DYRK1B ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DYRK1B: a dual-specificity protein kinase of the DYRK family. Localizes in the nucleus, where it enhances the transcriptional activity of TCF1/HNF1A. A co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression. Induced by members of the Rho-family in myoblasts. Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines. Contains a bipartite nuclear targeting signal sequence. Three splice-variant isoforms have been described.
Protein type: EC 2.7.12.1; Protein kinase, CMGC; Protein kinase, dual-specificity (non-receptor); Kinase, protein; CMGC group; DYRK family; Dyrk1 subfamily
Cellular Component: nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; transcription coactivator activity; transferase activity, transferring phosphorus-containing groups; protein serine/threonine/tyrosine kinase activity; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: positive regulation of transcription, DNA-dependent; phosphorylation; protein amino acid phosphorylation; myoblast fusion
Research Articles on DYRK1B
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Product Notes
The Mouse DYRK1B dyrk1b (Catalog #AAA9333340) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333340 ELISA Kit recognizes Mouse DYRK1B. It is sometimes possible for the material contained within the vial of "dual-specificity tyrosine- (Y) -phosphorylation regulated kinase 1B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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