Human deltex homolog 3 (Drosophila) ELISA Kit | DTX3 elisa kit
Human Protein deltex-3, DTX3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]
Uniprot Description
DTX3: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. Belongs to the Deltex family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.-; Ligase
Chromosomal Location of Human Ortholog: 12q13.3
Cellular Component: cytoplasm
Molecular Function: zinc ion binding; ligase activity
Biological Process: Notch signaling pathway; protein ubiquitination
Research Articles on DTX3
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Product Notes
The Human DTX3 dtx3 (Catalog #AAA9324964) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9324964 ELISA Kit recognizes Human DTX3. It is sometimes possible for the material contained within the vial of "deltex homolog 3 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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