SDS-PAGE
Desmoglein-3 (Dsg3) Recombinant Protein | Dsg3 recombinant protein
Recombinant Mouse Desmoglein-3 (Dsg3), partial
Gene Names
Dsg3; bal
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Desmoglein-3 (Dsg3); Recombinant Mouse Desmoglein-3 (Dsg3); partial; 130 kDa pemphigus vulgaris antigen homolog; Dsg3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
50-617aa;Partial
Sequence
EWVKFAKPCREREDNSRRNPIAKITSDFQKNQKITYRISGVGIDQPPFGIFVVDPNNGDINITAIVDREETPSFLITCRALNALGQDVERPLILTVKILDVNDNPPIFSQTIFKGEIEENSASNSLVMILNATDADEPNHMNSKIAFKIVSQEPAGMSMFLISRNTGEVRTLTSSLDREQISSYHLVVSGADNDGTGLSTQCECSIKIKDVNDNFPVLRESQYSARIEENTLNAELLRFQVTDWDEEYTDNWLAVYFFTSGNEGNWFEIETDPRTNEGILKVVKALDYEQVQSMQFSIAVRNKAEFHQSVISQYRVQSTPVTIQVIDVREGISFRPPSKTFTVQRGVSTNKLVGYILGTYQATDEDTGKAASSVRYVLGRNDGGLLVIDSKTAQIKFVKNIDRDSTFIVNKTISAEVLAIDENTGKTSTGTIYVEVPSFNENCPSVVLEKKDICTSSPSVTLSVRTLDRGKYTGPYTVSLEEQPLKLPVMWTITTLNATSALLQAQQQVSPGVYNVPVIVKDNQDGLCDTPESLTLTVCQCDDRSMCRAPIPSREPNTYGESSWRLGP
Species
Mus musculus (Mouse)
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for Dsg3 recombinant protein
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Product Categories/Family for Dsg3 recombinant protein
References
"cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen." Ishikawa H., Silos S.A., Tamai K., Copeland N.G., Gilbert D.J., Jenkins N.A., Uitto J. Mamm. Genome 5:803-804(1994)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
64.3 kDa
NCBI Official Full Name
Desmoglein-3
NCBI Official Synonym Full Names
desmoglein 3
NCBI Official Symbol
Dsg3
NCBI Official Synonym Symbols
bal
NCBI Protein Information
desmoglein-3
UniProt Protein Name
Desmoglein-3
Protein Family
UniProt Gene Name
Dsg3
UniProt Entry Name
DSG3_MOUSE
NCBI Description
This gene encodes a member of the cadherin family of proteins that forms an integral transmembrane component of desmosomes, the multiprotein complexes involved in cell adhesion, organization of the cytoskeleton, cell sorting and cell signaling. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Mice lacking the encoded protein exhibit loss of keratinocyte cell adhesion resulting in a phenotype that resembles that of patients with pemphigus vulgaris. This gene is located in a cluster of desmosomal cadherin genes on chromosome 18. [provided by RefSeq, Feb 2016]
Uniprot Description
DSG3: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Protein type: Membrane protein, integral; Cell adhesion
Cellular Component: cell junction; desmosome; integral to membrane; integral to plasma membrane; membrane; plasma membrane; spot adherens junction
Molecular Function: calcium ion binding; metal ion binding
Biological Process: cell adhesion; homophilic cell adhesion
Research Articles on Dsg3
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Product Notes
The Dsg3 dsg3 (Catalog #AAA1000327) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 50-617aa;Partial. The amino acid sequence is listed below: EWVKFAKPCR EREDNSRRNP IAKITSDFQK NQKITYRISG VGIDQPPFGI FVVDPNNGDI NITAIVDREE TPSFLITCRA LNALGQDVER PLILTVKILD VNDNPPIFSQ TIFKGEIEEN SASNSLVMIL NATDADEPNH MNSKIAFKIV SQEPAGMSMF LISRNTGEVR TLTSSLDREQ ISSYHLVVSG ADNDGTGLST QCECSIKIKD VNDNFPVLRE SQYSARIEEN TLNAELLRFQ VTDWDEEYTD NWLAVYFFTS GNEGNWFEIE TDPRTNEGIL KVVKALDYEQ VQSMQFSIAV RNKAEFHQSV ISQYRVQSTP VTIQVIDVRE GISFRPPSKT FTVQRGVSTN KLVGYILGTY QATDEDTGKA ASSVRYVLGR NDGGLLVIDS KTAQIKFVKN IDRDSTFIVN KTISAEVLAI DENTGKTSTG TIYVEVPSFN ENCPSVVLEK KDICTSSPSV TLSVRTLDRG KYTGPYTVSL EEQPLKLPVM WTITTLNATS ALLQAQQQVS PGVYNVPVIV KDNQDGLCDT PESLTLTVCQ CDDRSMCRAP IPSREPNTYG ESSWRLGP . It is sometimes possible for the material contained within the vial of "Desmoglein-3 (Dsg3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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