SDS-PAGE
Desmoglein-1 (DSG1) Recombinant Protein | DSG1 recombinant protein
Recombinant Human Desmoglein-1 (DSG1), partial
Gene Names
DSG1; DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Desmoglein-1 (DSG1); Recombinant Human Desmoglein-1 (DSG1); partial; Cadherin family member 4; Desmosomal glycoprotein 1; DSG1 recombinant protein
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
50-548. Partial-length of the Extracellular Domain
Sequence
EWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGP
Species
Homo sapiens(Human)
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for DSG1 recombinant protein
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Product Categories/Family for DSG1 recombinant protein
References
"Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules."Wheeler G.N., Parker A.E., Thomas C.L., Ataliotis P., Poynter D., Arnemann J., Rutman A.J., Pidsley S.C., Watt F.M., Rees D.A., Buxton R.S., Magee A.I.Proc. Natl. Acad. Sci. U.S.A. 88:4796-4800(1991)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60.4 kDa
NCBI Official Full Name
desmoglein-1 preproprotein
NCBI Official Synonym Full Names
desmoglein 1
NCBI Official Symbol
DSG1
NCBI Official Synonym Symbols
DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA
NCBI Protein Information
desmoglein-1
UniProt Protein Name
Desmoglein-1
Protein Family
UniProt Gene Name
DSG1
UniProt Synonym Gene Names
CDHF4; DG1; DGI
NCBI Description
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
Uniprot Description
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Research Articles on DSG1
Similar Products
Product Notes
The DSG1 dsg1 (Catalog #AAA7053575) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 50-548. Partial-length of the Extracellular Domain. The amino acid sequence is listed below: EWIKFAAACR EGEDNSKRNP IAKIHSDCAA NQQVTYRISG VGIDQPPYGI FVINQKTGEI NITSIVDREV TPFFIIYCRA LNSMGQDLER PLELRVRVLD INDNPPVFSM ATFAGQIEEN SNANTLVMIL NATDADEPNN LNSKIAFKII RQEPSDSPMF IINRNTGEIR TMNNFLDREQ YGQYALAVRG SDRDGGADGM SAECECNIKI LDVNDNIPYM EQSSYTIEIQ ENTLNSNLLE IRVIDLDEEF SANWMAVIFF ISGNEGNWFE IEMNERTNVG ILKVVKPLDY EAMQSLQLSI GVRNKAEFHH SIMSQYKLKA SAISVTVLNV IEGPVFRPGS KTYVVTGNMG SNDKVGDFVA TDLDTGRPST TVRYVMGNNP ADLLAVDSRT GKLTLKNKVT KEQYNMLGGK YQGTILSIDD NLQRTCTGTI NINIQSFGND DRTNTEPNTK ITTNTGRQES TSSTNYDTST TSTDSSQVYS SEPGNGAKDL LSDNVHFGP . It is sometimes possible for the material contained within the vial of "Desmoglein-1 (DSG1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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