Donkey Keratin, Type II Cuticular Hb6 (KRT86) ELISA Kit | KRT86 elisa kit
Donkey Keratin, Type II Cuticular Hb6 (KRT86) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a type II keratin protein, which heterodimerizes with type I keratins to form hair and nails. This gene is present in a cluster of related genes and pseudogenes on chromosome 12. Mutations in this gene have been observed in patients with the hair disease monilethrix. [provided by RefSeq, Feb 2016]
Uniprot Description
K86: Defects in KRT86 are a cause of monilethrix (MLTRX). Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected. Belongs to the intermediate filament family.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: extracellular space; keratin filament
Molecular Function: protein binding; structural molecule activity
Disease: Monilethrix
Research Articles on KRT86
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Product Notes
The Donkey KRT86 krt86 (Catalog #AAA9358250) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9358250 ELISA Kit recognizes Donkey KRT86. It is sometimes possible for the material contained within the vial of "Keratin, Type II Cuticular Hb6 (KRT86), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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