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STAM2 blocking peptide

STAM2 Immunizing Peptide

Gene Names
STAM2; Hbp; STAM2A; STAM2B
Reactivity
Human, Mouse, Dog
Synonyms
STAM2; STAM2 Immunizing Peptide; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; HGNC: 11358; DKFZp564C047; Hbp; STAM2A; STAM2B; STAM-like protein containing SH3 and ITAM domains 2; signal transducing adaptor molecule 2; STAM2 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Dog
Form/Format
100ug of dried peptide
Sequence
C-QSIDPTDSKPDSQD
Sequence Length
525
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,370 Da
NCBI Official Full Name
signal transducing adaptor molecule 2
NCBI Official Synonym Full Names
signal transducing adaptor molecule 2
NCBI Official Symbol
STAM2
NCBI Official Synonym Symbols
Hbp; STAM2A; STAM2B
NCBI Protein Information
signal transducing adapter molecule 2
UniProt Protein Name
Signal transducing adapter molecule 2
UniProt Gene Name
STAM2
UniProt Synonym Gene Names
HBP; STAM-2
UniProt Entry Name
STAM2_HUMAN

NCBI Description

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]

Uniprot Description

STAM2: an adaptor protein involved in the downstream signaling of cytokine receptors. Contain a SH3 domain and immunoreceptor tyrosine-based activation motif (ITAM). Acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. May modulate the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2q23.3

Cellular Component: cytoplasm; cytosol; early endosome membrane; intracellular membrane-bound organelle; nucleoplasm

Molecular Function: protein binding

Biological Process: autophagy; endosome transport; intracellular protein transport; negative regulation of epidermal growth factor receptor signaling pathway

Research Articles on STAM2

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Product Notes

The STAM2 stam2 (Catalog #AAA425121) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The STAM2 Immunizing Peptide reacts with Human, Mouse, Dog and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-QSIDPTDS KPDSQD. It is sometimes possible for the material contained within the vial of "STAM2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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