APOM blocking peptide
APOM Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
Uniprot Description
APOM: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Plasma protein. Expressed in liver and kidney. Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6p21.33
Cellular Component: extracellular region; integral to plasma membrane
Molecular Function: antioxidant activity; lipid transporter activity; phospholipid binding
Biological Process: cholesterol efflux; cholesterol homeostasis; lipoprotein metabolic process; response to glucose stimulus; retinoid metabolic process; reverse cholesterol transport