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Dedicator of cytokinesis protein 3 (Dock3) Recombinant Protein | Dock3 recombinant protein

Recombinant Mouse Dedicator of cytokinesis protein 3 (Dock3) , partial

Gene Names
Dock3; PBP; MOCA; mKIAA0299
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Dedicator of cytokinesis protein 3 (Dock3); Recombinant Mouse Dedicator of cytokinesis protein 3 (Dock3); partial; Dock3 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Length
2,027
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
232,910 Da
NCBI Official Full Name
Dedicator of cytokinesis protein 3
NCBI Official Synonym Full Names
dedicator of cyto-kinesis 3
NCBI Official Symbol
Dock3
NCBI Official Synonym Symbols
PBP; MOCA; mKIAA0299
NCBI Protein Information
dedicator of cytokinesis protein 3
UniProt Protein Name
Dedicator of cytokinesis protein 3
UniProt Gene Name
Dock3
UniProt Synonym Gene Names
Moca; PBP

Uniprot Description

Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of amyloid-beta APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors.

Research Articles on Dock3

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Product Notes

The Dock3 dock3 (Catalog #AAA1487080) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Dedicator of cytokinesis protein 3 (Dock3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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