ERAD-associated E3 ubiquitin-protein ligase doa10 (doa10) Recombinant Protein | doa10 recombinant protein
Recombinant Schizosaccharomyces pombe ERAD-associated E3 ubiquitin-protein ligase doa10 (doa10), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
ERAD-associated E3 ubiquitin-protein ligase doa10 (doa10); Recombinant Schizosaccharomyces pombe ERAD-associated E3 ubiquitin-protein ligase doa10 (doa10); partial; doa10 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Length
1242
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
142,366 Da
NCBI Official Full Name
ER-localized ubiquitin ligase Doa10 (predicted)
NCBI Official Symbol
doa10
NCBI Protein Information
ER-localized ubiquitin ligase Doa10 (predicted)
UniProt Protein Name
ERAD-associated E3 ubiquitin-protein ligase doa10
UniProt Gene Name
doa10
UniProt Synonym Gene Names
ssm4
Uniprot Description
E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated E2 ligases, and transfers it to substrates promoting their degradation. Mediates the degradation of a broad range of substrates, including endoplasmic reticulum membrane proteins (ERQC), soluble nuclear proteins and soluble cytoplasmic proteins (CytoQC). Component of the doa10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains. Also recognizes the N-terminally acetylated residue of proteins as degradation signal (degron).
Similar Products
Product Notes
The doa10 doa10 (Catalog #AAA1096784) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ERAD-associated E3 ubiquitin-protein ligase doa10 (doa10), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
