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DnaJ homolog subfamily B member 4 (DNAJB4) Recombinant Protein | DNAJB4 recombinant protein

Recombinant Human DnaJ homolog subfamily B member 4 (DNAJB4)

Gene Names
DNAJB4; DjB4; HLJ1; DNAJW
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
DnaJ homolog subfamily B member 4 (DNAJB4); Recombinant Human DnaJ homolog subfamily B member 4 (DNAJB4); DNAJB4 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-337, Full length protein
Sequence
GKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS
Sequence Length
336
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,807 Da
NCBI Official Full Name
dnaJ homolog subfamily B member 4 isoform a
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member B4
NCBI Official Symbol
DNAJB4
NCBI Official Synonym Symbols
DjB4; HLJ1; DNAJW
NCBI Protein Information
dnaJ homolog subfamily B member 4
UniProt Protein Name
DnaJ homolog subfamily B member 4
Protein Family
UniProt Gene Name
DNAJB4
UniProt Synonym Gene Names
DNAJW; HLJ1; HSP40 homolog; Heat shock protein 40 homolog

NCBI Description

The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Uniprot Description

Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).

Research Articles on DNAJB4

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Product Notes

The DNAJB4 dnajb4 (Catalog #AAA1364349) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-337, Full length protein. The amino acid sequence is listed below: GKDYYCILGI EKGASDEDIK KAYRKQALKF HPDKNKSPQA EEKFKEVAEA YEVLSDPKKR EIYDQFGEEG LKGGAGGTDG QGGTFRYTFH GDPHATFAAF FGGSNPFEIF FGRRMGGGRD SEEMEIDGDP FSAFGFSMNG YPRDRNSVGP SRLKQDPPVI HELRVSLEEI YSGCTKRMKI SRKRLNADGR SYRSEDKILT IEIKKGWKEG TKITFPREGD ETPNSIPADI VFIIKDKDHP KFKRDGSNII YTAKISLREA LCGCSINVPT LDGRNIPMSV NDIVKPGMRR RIIGYGLPFP KNPDQRGDLL IEFEVSFPDT ISSSSKEVLR KHLPAS. It is sometimes possible for the material contained within the vial of "DnaJ homolog subfamily B member 4 (DNAJB4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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