Human dynein, axonemal, heavy chain 2 ELISA Kit | DNAH2 elisa kit
Human Dynein heavy chain 2, axonemal, DNAH2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]
Uniprot Description
DNAH2: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Belongs to the dynein heavy chain family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: microtubule; axonemal dynein complex
Molecular Function: ATPase activity; microtubule motor activity; ATP binding
Biological Process: metabolic process; ciliary or flagellar motility; microtubule-based movement
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Product Notes
The Human DNAH2 dnah2 (Catalog #AAA9342693) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342693 ELISA Kit recognizes Human DNAH2. It is sometimes possible for the material contained within the vial of "dynein, axonemal, heavy chain 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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