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Dystrophia Myotonica Protein Kinase Recombinant Protein | DMPK recombinant protein

Recombinant Dystrophia Myotonica Protein Kinase (DMPK)

Gene Names
Dmpk; DM; DMK; Dm15; MDPK; MT-PK
Applications
SDS-Page, Western Blot
Purity
>90%
Synonyms
Dystrophia Myotonica Protein Kinase; Recombinant Dystrophia Myotonica Protein Kinase (DMPK); DM; DM1; DM1PK; DMK; MDPK; MT-PK; Myotonic Dystrophy Protein Kinase; Myotonin-Protein Kinase; Dystrophia Myotonica 1; Thymopoietin Homolog; DMPK recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
>90%
Form/Format
Freeze-dried powder
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Met1~Lys109
Sequence Length
537
Applicable Applications for DMPK recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Source
Prokaryotic expression
Species
Mouse
Tag
N-terminal His Tag
Subcellular Location
Endoplasmic reticulum lumen
Isoelectric Point
6.7
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for DMPK recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted Molecular Mass: 16.1kDa
Accurate Molecular Mass: 16kDa
NCBI Official Full Name
myotonin-protein kinase isoform 3
NCBI Official Synonym Full Names
dystrophia myotonica-protein kinase
NCBI Official Symbol
Dmpk
NCBI Official Synonym Symbols
DM; DMK; Dm15; MDPK; MT-PK
NCBI Protein Information
myotonin-protein kinase
UniProt Protein Name
Myotonin-protein kinase
Protein Family
UniProt Gene Name
Dmpk
UniProt Synonym Gene Names
Dm15; Mdpk; MT-PK; DMK; MDPK
UniProt Entry Name
DMPK_MOUSE

NCBI Description

The protein encoded by this gene is a serine/threonine protein kinase that contains coiled-coil and C-terminal membrane association domains. In the embryonic mouse, it is found in cardiac and skeletal myocytes where it appears to play a role in myogenesis. In adults, the transcript is localized to several tissues including brain, heart, and skeletal and smooth muscle, and a function in cytoskeletal remodeling has been described. Transcripts with expanded CUG repeats in the 3' untranslated region mediate alternative splicing of several genes and sequester RNA binding proteins and RNA transcripts that contain CAG repeats, resulting in myotonic dystrophy, an autosomal dominant neuromuscular disorder. Alternative splicing results in multiple protein coding and non-coding transcript variants. [provided by RefSeq, Oct 2014]

Research Articles on DMPK

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Product Notes

The DMPK dmpk (Catalog #AAA2122988) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1~Lys109. AAA Biotech's Dystrophia Myotonica Protein Kinase can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the DMPK dmpk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dystrophia Myotonica Protein Kinase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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