Delta-like protein 1 Recombinant Protein | DLL1 recombinant protein
Delta-like protein 1
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]
Uniprot Description
DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.
Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell development/differentiation
Chromosomal Location of Human Ortholog: 6q27
Cellular Component: adherens junction; apical plasma membrane; lipid raft; plasma membrane
Molecular Function: Notch binding; protein binding; Tat protein binding
Biological Process: astrocyte development; cell differentiation; cerebellar molecular layer formation; cerebellar Purkinje cell layer structural organization; determination of left/right symmetry; heart looping; lateral inhibition; marginal zone B cell differentiation; negative regulation of cell differentiation; negative regulation of cell proliferation; negative regulation of epidermal cell differentiation; negative regulation of epithelial cell differentiation; negative regulation of interleukin-10 production; negative regulation of myoblast differentiation; negative regulation of neuron differentiation; neuron fate specification; Notch receptor processing; Notch signaling pathway; organ growth; positive regulation of cell proliferation; positive regulation of endocytosis; positive regulation of Notch signaling pathway; positive regulation of skeletal muscle growth; positive regulation of transcription from RNA polymerase II promoter; proximal/distal pattern formation; regulation of blood pressure; regulation of cell adhesion; regulation of cell division; regulation of growth; regulation of neurogenesis; regulation of skeletal muscle growth; regulation of somitogenesis; retina development in camera-type eye; retina morphogenesis in camera-type eye; skeletal muscle growth; somitogenesis; spinal cord development
Research Articles on DLL1
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Product Notes
The DLL1 dll1 (Catalog #AAA7042621) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-723aa; full length protein. The amino acid sequence is listed below: QVWSSGVFEL KLQEFVNKKG LLGNRNCCRG GAGPPPCACR TFFRVCLKHY QASVSPEPPC TYGSAVTPVL GVDSFSLPDG GGADSAFSNP IRFPFGFTWP GTFSLIIEAL HTDSPDDLAT ENPERLISRL ATQRHLTVGE EWSQDLHSSG RTDLKYSYRF VCDEHYYGEG CSVFCRPRDD AFGHFTCGER GEKVCNPGWK GPYCTEPICL PGCDEQHGFC DKPGECKCRV GWQGRYCDEC IRYPGCLHGT CQQPWQCNCQ EGWGGLFCNQ DLNYCTHHKP CKNGATCTNT GQGSYTCSCR PGYTGATCEL GIDECDPSPC KNGGSCTDLE NSYSCTCPPG FYGKICELSA MTCADGPCFN GGRCSDSPDG GYSCRCPVGY SGFNCEKKID YCSSSPCSNG AKCVDLGDAY LCRCQAGFSG RHCDDNVDDC ASSPCANGGT CRDGVNDFSC TCPPGYTGRN CSAPVSRCEH APCHNGATCH ERGHRYVCEC ARGYGGPNCQ FLLPELPPGP AVVDLTEKLE GQGGPFPWVA VCAGVILVLM LLLGCAAVVV CVRLRLQKHR PPADPCRGET ETMNNLANCQ REKDISVSII GATQIKNTNK KADFHGDHSA DKNGFKARYP AVDYNLVQDL KGDDTAVRDA HSKRDTKCQP QGSSGEEKGT PTTLRGGEAS ERKRPDSGCS TSKDTKYQSV YVISEEKDEC VIATEV. It is sometimes possible for the material contained within the vial of "Delta-like protein 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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