SDS-PAGE
Probable dimethyladenosine transferase Recombinant Protein | DIMT1 recombinant protein
Recombinant Human Probable dimethyladenosine transferase
Gene Names
DIMT1; DIM1; DIMT1L; HUSSY5; HSA9761
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Probable dimethyladenosine transferase; Recombinant Human Probable dimethyladenosine transferase; DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1-like; Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; Probable 18S rRNA dimethylase; Probable S-adenosylmethionine-6-N'; N'-adenosyl(rRNA) dimethyltransferase; DIMT1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-313aa; Full Length
Sequence
MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS
Sequence Length
313
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for DIMT1 recombinant protein
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.
Product Categories/Family for DIMT1 recombinant protein
References
Wei Y.J., Ding J.F., Liu Y.Q., Xu Y.Y., Hui R.T., Sheng H., Zhao X.W., Jiang Y.X., Liu D.Q., Zhao Y., Cao H.Q., Meng X.M., Liu S.
Characterization of 16 novel human genes showing high similarity to yeast sequences.Stanchi F., Bertocco E., Toppo S., Dioguardi R., Simionati B., Cannata N., Zimbello R., Lanfranchi G., Valle G.3.0.CO;2-H>Yeast 18:69-80(2001)
Full-insert sequence of mapped XREF EST.Barrow I.K.-P., Boguski M.S., Touchman J.W., Spencer F.Functional proteomic analysis of human nucleolus.Scherl A., Coute Y., Deon C., Calle A., Kindbeiter K., Sanchez J.-C., Greco A., Hochstrasser D.F., Diaz J.-J.Mol. Biol. Cell 13:4100-4109(2002)
Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17(2011)
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012)
Crystal structure of human dimethyladenosine transferase with SAM.Structural genomics consortium (SGC)
Submitted (MAY-2005)
to the PDB data bank
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51.2 kDa
NCBI Official Full Name
probable dimethyladenosine transferase
NCBI Official Synonym Full Names
DIM1 dimethyladenosine transferase 1 homolog
NCBI Official Symbol
DIMT1
NCBI Official Synonym Symbols
DIM1; DIMT1L; HUSSY5; HSA9761
NCBI Protein Information
probable dimethyladenosine transferase
UniProt Protein Name
Probable dimethyladenosine transferase
Protein Family
UniProt Gene Name
DIMT1
UniProt Synonym Gene Names
DIMT1L
UniProt Entry Name
DIM1_HUMAN
Uniprot Description
DIMT1: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein type: Methyltransferase; Nucleolus; RNA-binding; EC 2.1.1.183
Chromosomal Location of Human Ortholog: 5q12.1
Cellular Component: cytoplasm; nucleolus; nucleus
Molecular Function: rRNA (adenine-N6,N6-)-dimethyltransferase activity
Biological Process: rRNA methylation
Research Articles on DIMT1
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Product Notes
The DIMT1 dimt1 (Catalog #AAA1338546) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-313aa; Full Length. The amino acid sequence is listed below: MPKVKSGAIG RRRGRQEQRR ELKSAGGLMF NTGIGQHILK NPLIINSIID KAALRPTDVV LEVGPGTGNM TVKLLEKAKK VVACELDPRL VAELHKRVQG TPVASKLQVL VGDVLKTDLP FFDTCVANLP YQISSPFVFK LLLHRPFFRC AILMFQREFA LRLVAKPGDK LYCRLSINTQ LLARVDHLMK VGKNNFRPPP KVESSVVRIE PKNPPPPINF QEWDGLVRIT FVRKNKTLSA AFKSSAVQQL LEKNYRIHCS VHNIIIPEDF SIADKIQQIL TSTGFSDKRA RSMDIDDFIR LLHGFNAEGI HFS. It is sometimes possible for the material contained within the vial of "Probable dimethyladenosine transferase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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