IF (Immunofluorescence)
(Immunofluorescent analysis of HepG2 cells using at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human PITX3 Polyclonal Antibody | anti-PITX3 antibody
PITX3 Antibody, Biotin conjugated
Gene Names
PITX3; ASMD; ASOD; PTX3; CTPP4; CTRCT11
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
PITX3, Antibody; PITX3 Antibody, Biotin conjugated; Pituitary homeobox 3; Homeobox protein PITX3; Paired-like homeodomain transcription factor 3; PITX3; PTX3; anti-PITX3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
302
Applicable Applications for anti-PITX3 antibody
ELISA
Immunogen
Recombinant human Pituitary homeobox 3 protein (10-200AA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Biotin
Preparation and Storage
Upon receipt, aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IF (Immunofluorescence)
(Immunofluorescent analysis of HepG2 cells using at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IF (Immunofluorescence)
(Immunofluorescent analysis of HepG2 cells using at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
WB (Western Blot)
(Western BlotPositive WB detected in: Rat lung tissue, Mouse lung tissueAll lanes: HTR3A antibody at 2.5 g/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 56, 59, 54, 60 kDaObserved band size: 56 kDa)
WB (Western Blot)
(Western BlotPositive WB detected in: Rat lung tissue, Mouse lung tissueAll lanes: HTR3A antibody at 2.5 g/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 56, 59, 54, 60 kDaObserved band size: 56 kDa)
Related Product Information for anti-PITX3 antibody
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. Acts by decreasing the interaction of NR4A2/NURR1 with the corepressor NCOR2/SMRT which acts through histone deacetylases (HDACs) to keep promoters of NR4A2/NURR1 target genes in a repressed deacetylated state. Essential for the normal lens development and differentiation. Plays a critical role in the maintenance of mitotic activity of lens epithelial cells, fiber cell differentiation and in the control of the temporal and spatial activation of fiber cell-specific crystallins. Positively regulates FOXE3 expression and negatively regulates PROX1 in the anterior lens epithelium, preventing activation of CDKN1B/P27Kip1 and CDKN1C/P57Kip2 and thus maintains lens epithelial cells in cell cycle (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,832 Da
NCBI Official Full Name
pituitary homeobox 3
NCBI Official Synonym Full Names
paired like homeodomain 3
NCBI Official Symbol
PITX3
NCBI Official Synonym Symbols
ASMD; ASOD; PTX3; CTPP4; CTRCT11
NCBI Protein Information
pituitary homeobox 3
UniProt Protein Name
Pituitary homeobox 3
UniProt Gene Name
PITX3
UniProt Synonym Gene Names
PTX3
UniProt Entry Name
PITX3_HUMAN
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Product Notes
The PITX3 pitx3 (Catalog #AAA232532) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PITX3 Antibody, Biotin conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PITX3 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the PITX3 pitx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PITX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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