Apolipoprotein AI/B (Apo AI/B) Calibrator 3 Native Protein | Apoa1 native protein

Apo AI/B Calibrator 3

Cat. Num. AAA318223

• Gene Names: Apoa1; apoA-I
• Purity: Multi-step precipitation; Product is 0.2um filtered.
• Synonyms: Apolipoprotein AI/B (Apo AI/B) Calibrator 3; Apo AI/B Calibrator 3; Apolipoprotein AI/B Calibrator 3; Apoa1 native protein

• Host: Defibrinated Human Plasma
• Specificity: Apolipoprotein AI/B (Apo AI/B) Calibrator 3
• Purity/Purification: Multi-step precipitation; Product is 0.2um filtered.
• Form/Format: Purified, Liquid
• Concentration: Total protein: 3.1g/dL (Biuret: Cobas-Mira); Apo AI: 312mg/dL; Apo B: 312mg/dL (Turbidimetric Assay (Cobas-Mira) (varies by lot)

• Inactivation: Not applicable.
• Buffer: 0.1M Sodium borate, 0.2M Sodium chloride containing proprietary stabilizers
• Preservative: 0.1% Sodium azide
• Warnings: All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infecti
• Preparation and Storage: Short term, store at 2 to 8 degree C. Long term, store at -20 degree C. Avoid multiple freeze/thaw cycles.

Product Categories/Family for Apoa1 native protein

Purified Lipoproteins

NCBI and Uniprot Product Information

• NCBI GI #: 6978515
• NCBI GeneID: 25081
• NCBI Accession #: NP_036870.1
• NCBI GenBank Nucleotide #: NM_012738.1
• UniProt Accession #: P04639; O08877; O09054; Q5EBB2
• Molecular Weight: 30,062 Da
• NCBI Official Full Name: apolipoprotein A-I preproprotein
• NCBI Official Synonym Full Names: apolipoprotein A-I
• NCBI Official Symbol: Apoa1
• NCBI Official Synonym Symbols: apoA-I
• NCBI Protein Information: apolipoprotein A-I; apo-AI; apolipoprotein A1; apolipoprotein A-1; preproapolipoprotein A-I
• UniProt Protein Name: Apolipoprotein A-I
• Protein Family: Apolipoprotein
• UniProt Gene Name: Apoa1
• UniProt Entry Name: APOA1_RAT

NCBI Description

major component of high density lipoprotein (HDL) that is involved in intercellular cholesterol transport in astrocytes; cofactor for lecithin cholesterolacyltransferase (LCAT) [RGD]

Uniprot Description

Function: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

Subunit structure: Interacts with APOA1BP and CLU. Component of a sperm activating protein complex (SPAP), consisting of APOA1, an immunoglobulin heavy chain, an immunoglobulin light chain and albumin

Subcellular location: Secreted.

Tissue specificity: Major protein of plasma HDL, also found in chylomicrons.

Post-translational modification: Phosphorylation sites are present in the extracelllular medium

Sequence similarities: Belongs to the apolipoprotein A1/A4/E family.