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Defensin Alpha 3, Neutrophil Specific (DEFa3) Recombinant Protein | DEFa3 recombinant protein

Recombinant Defensin Alpha 3, Neutrophil Specific (DEFa3)

Gene Names
DEFA3; HP3; DEF3; HNP3; HP-3; HNP-3
Applications
SDS-Page, Western Blot
Purity
> 90%
Synonyms
Defensin Alpha 3; Neutrophil Specific (DEFa3); Recombinant Defensin Alpha 3; HNP3; DEF3; HNP-2; Neutrophil defensin 2; DEFa3 recombinant protein
Ordering
For Research Use Only!
Host
Host: E Coli
Source: Prokaryotic Expression
Purity/Purification
> 90%
Form/Format
Freeze-Dried Powder; PBS, pH7.4, Containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Glu20~Cys94
Sequence Length
94
Applicable Applications for DEFa3 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Species
Mouse
Tag
N-terminal His-Tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Subcellular Location
Secreted
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for DEFa3 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
Predicted MW: 14.98kDa
Accurate MW: 18kDa
NCBI Official Full Name
defensin, alpha 3, neutrophil-specific
NCBI Official Synonym Full Names
defensin alpha 3
NCBI Official Symbol
DEFA3
NCBI Official Synonym Symbols
HP3; DEF3; HNP3; HP-3; HNP-3
NCBI Protein Information
neutrophil defensin 3
Protein Family

NCBI Description

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, Oct 2014]

Research Articles on DEFa3

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Product Notes

The DEFa3 (Catalog #AAA2105496) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Glu20~Cys94. AAA Biotech's Defensin Alpha 3, Neutrophil Specific (DEFa3) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the DEFa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Defensin Alpha 3, Neutrophil Specific (DEFa3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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