Hamster Dopamine Decarboxylase ELISA Kit | DDC elisa kit
Hamster Dopamine Decarboxylase ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span. Ref.4
Catalytic activity: L-dopa = dopamine + CO2.5-hydroxy-L-tryptophan = 5-hydroxytryptamine + CO2.
Cofactor: Pyridoxal phosphate.
Subunit structure: Homodimer.
Tissue specificity: Hypoderm isoform isexpressed only in hypodermal epithelium and the CNS isoform onlyin central nervous system. Ref.1 Ref.10
Developmental stage: Hypoderm isoform hashigh expression levels in hypoderm during late embryogenesis, late larval development, pupariation and adult eclosion. CNS isoform hasconstant expression level in CNS throughout the life cycle. Ref.10 Ref.11
Induction: By ecdysone. In larval epidermis, expression is rapidly induced. In adult epidermis expression responds to a pulse of hormone and there is a time lag between initial exposure and appearance of DDC. Ref.12
Polymorphism: Three common molecular polymorphisms (2 in the promoter region and Phe-12) account for 15.5% of the genetic contribution to variance in life span, the polymorphisms are maintained by balancing selection.
Sequence similarities: Belongs to the group II decarboxylase family.
Research Articles on DDC
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Product Notes
The Hamster DDC ddc (Catalog #AAA016480) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA016480 ELISA Kit recognizes Hamster DDC. It is sometimes possible for the material contained within the vial of "Dopamine Decarboxylase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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