Early E2A DNA-binding protein (DBP) Recombinant Protein | DBP recombinant protein
Recombinant Human adenovirus E serotype 4 Early E2A DNA-binding protein (DBP), partial
NCBI and Uniprot Product Information
Uniprot Description
Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. Also enhances the rate of initiation. Released from template upon second strand synthesis. Assembles in complex with viral pTP, viral pol, host NFIA and host POU2F1/OCT1 on viral origin of replication. Covers the whole ssDNA genome during synthesis. The complementary strand synthesis induces its relese from DNA template. May inhibit cellular transcription mediated by the interaction between host SRCAP and CBP.
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Product Notes
The DBP dbp (Catalog #AAA1092382) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 106-512aa; Partial. The amino acid sequence is listed below: EELGAVGFSY PPVRITGKDG KRSFETLNEN DPLTKAASAK MAVTNPLSLP IVSAWEKGME IMNMLMERYR VESDLKSNFQ LMPEQGEVYR RICHLYINEE HRGIPLTFTS NKTLTTMMGR FLQGFVHAHS QIAHKNWEST GCALWLHGCT EVEGKLRCLH GTTMIQKEHM IEMDVASENG QRALKENPDR AKVTQNRWGR SVVQLANNDA RCCVHDAGCA TNQFSSKSCG VFFTEGAKAQ QAFKQLEAFM KAMYPGMNAD QAQVMLIPLH CDCNHKPGCV PTMGRQTCKM TPFGMANAED LDVDGITDAT VLASVKHPAL MVFQCCNPVY RNSRAQNAGP NCDFKISAPD LLGALQLTRK LWTDSFPDTL LPKLLIPEFK WLAKYQFRNV SLPAGHAETS RQNPFDF . It is sometimes possible for the material contained within the vial of "Early E2A DNA-binding protein (DBP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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