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Testing Data

anti-Human Cytochrome P450 4V2 Antibody | anti-CYP4V2 antibody

Cytochrome P450 4V2 Antibody

Gene Names
CYP4V2; BCD; CYP4AH1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Cytochrome P450 4V2; Cytochrome P450 4V2 Antibody; BCD; CP4V2; CYP4AH1; cytochrome P450; family 4; subfamily V; polypeptide 2; FLJ18432; MGC43534; anti-CYP4V2 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
CYP4V2 antibody detects endogenous levels of total CYP4V2protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
525
Applicable Applications for anti-CYP4V2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:3000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from Internal of human CYP4V2.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

Testing Data
References
Li A., Am. J. Hum. Genet. 74:817-826(2004). Ota T., Nat. Genet. 36:40-45(2004). Hillier L.W., Nature 434:724-731(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58,166 Da
NCBI Official Full Name
cytochrome P450 4V2
NCBI Official Synonym Full Names
cytochrome P450 family 4 subfamily V member 2
NCBI Official Symbol
CYP4V2
NCBI Official Synonym Symbols
BCD; CYP4AH1
NCBI Protein Information
cytochrome P450 4V2
UniProt Protein Name
Cytochrome P450 4V2
Protein Family
UniProt Gene Name
CYP4V2

NCBI Description

This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids. Mutations in this gene result in Bietti crystalline corneoretinal dystrophy. [provided by RefSeq, Jul 2008]

Uniprot Description

Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye (PubMed:19661213, PubMed:22772592). Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12) (PubMed:19661213). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:22772592). Also produces some 21-hydroxydocosahexaenoate. Also converts eicosapentaenoate (EPA) to 20-hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:22772592).

Research Articles on CYP4V2

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Product Notes

The CYP4V2 cyp4v2 (Catalog #AAA858394) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Cytochrome P450 4V2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytochrome P450 4V2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:3000 ELISA: 1:20000. Researchers should empirically determine the suitability of the CYP4V2 cyp4v2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytochrome P450 4V2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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