Mouse cytochrome P450, family 2, subfamily R, polypeptide 1 ELISA Kit | CYP2R1 elisa kit
Mouse Vitamin D 25-hydroxylase, CYP2R1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
CYP2R1: Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3). Defects in CYP2R1 are the cause of rickets vitamin D- dependent type 1B (VDDR1B); also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. A disorder caused by a selective deficiency of the active form of vitamin D (1,25-dihydroxyvitamin D3) and resulting in defective bone mineralization and clinical features of rickets. The patients sera have low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activityand low levels of 25-hydroxyvitamin D. Belongs to the cytochrome P450 family.
Protein type: Oxidoreductase; EC 1.14.13.15
Cellular Component: membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm
Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; cholestanetriol 26-monooxygenase activity; metal ion binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; steroid hydroxylase activity; oxidoreductase activity; oxygen binding; monooxygenase activity; vitamin D3 25-hydroxylase activity
Biological Process: organic acid metabolic process; xenobiotic metabolic process; exogenous drug catabolic process; vitamin D metabolic process
Research Articles on CYP2R1
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Product Notes
The Mouse CYP2R1 cyp2r1 (Catalog #AAA9339482) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339482 ELISA Kit recognizes Mouse CYP2R1. It is sometimes possible for the material contained within the vial of "cytochrome P450, family 2, subfamily R, polypeptide 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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