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Cytochrome P450 11B1, mitochondrial (CYP11B1) Recombinant Protein | CYP11B1 recombinant protein

Recombinant Guinea pig Cytochrome P450 11B1, mitochondrial (CYP11B1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cytochrome P450 11B1; mitochondrial (CYP11B1); Recombinant Guinea pig Cytochrome P450 11B1; CYP11B1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
25-500, Full length protein
Sequence
GTRAVTASKASVLPFEVIPQHQGNKRQRVLQFWKEQNHDDLHLEMHQTFQELGPIFRCDVGSTRIVAVMLPEDCARLHQAESPYPHRMHLEPWMAYREHRRQNLGVFLLNGPEWLSNRRWLNPNVLSPKAVQNLLPMVDTVARDFSEALKQKVLQSAQGSLTMDMQPDIHKYTVEVSNFALFGERLGLFGCNPSSQSLKFIHALEAVFKTTTQLMFLPRSLSRWMRSQAWKEHFEAWDYISEYAENRIQKKYEELARGCSQYNSIVANLMLQGNLPLRAMKANIMDLVAGSVDTTALPLMMTLFELARNPTVQQALRQESMATEPNIYENPQRLRMELPLLWAAIKETLRMYPVGLFLERFLTSPLVLQNYHIPAGTLVHLNLYSMGRNPEVFLSPEHYNPQRWLENKETYKHLAFGFGVRQCIGRRLAEVEMLLFLHHVLKSFCVETAFQEDVKFAYRFVMMPTSAPLLTFRPVS
Sequence Length
476
Species
Cavia porcellus (Guinea pig)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for CYP11B1 recombinant protein
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,820 Da
NCBI Official Full Name
cytochrome P450 11B1, mitochondrial
NCBI Official Symbol
Cyp11b1
NCBI Protein Information
cytochrome P450 11B1, mitochondrial
UniProt Protein Name
Cytochrome P450 11B1, mitochondrial
Protein Family
UniProt Gene Name
CYP11B1

Uniprot Description

Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.

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Product Notes

The CYP11B1 cyp11b1 (Catalog #AAA1401440) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 25-500, Full length protein. The amino acid sequence is listed below: GTRAVTASKA SVLPFEVIPQ HQGNKRQRVL QFWKEQNHDD LHLEMHQTFQ ELGPIFRCDV GSTRIVAVML PEDCARLHQA ESPYPHRMHL EPWMAYREHR RQNLGVFLLN GPEWLSNRRW LNPNVLSPKA VQNLLPMVDT VARDFSEALK QKVLQSAQGS LTMDMQPDIH KYTVEVSNFA LFGERLGLFG CNPSSQSLKF IHALEAVFKT TTQLMFLPRS LSRWMRSQAW KEHFEAWDYI SEYAENRIQK KYEELARGCS QYNSIVANLM LQGNLPLRAM KANIMDLVAG SVDTTALPLM MTLFELARNP TVQQALRQES MATEPNIYEN PQRLRMELPL LWAAIKETLR MYPVGLFLER FLTSPLVLQN YHIPAGTLVH LNLYSMGRNP EVFLSPEHYN PQRWLENKET YKHLAFGFGV RQCIGRRLAE VEMLLFLHHV LKSFCVETAF QEDVKFAYRF VMMPTSAPLL TFRPVS. It is sometimes possible for the material contained within the vial of "Cytochrome P450 11B1, mitochondrial (CYP11B1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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