Coupling of ubiquitin conjugation to ER degradation protein 1 (CUE1) Recombinant Protein | CUE1 recombinant protein
Recombinant Debaryomyces hansenii Coupling of ubiquitin conjugation to ER degradation protein 1 (CUE1)
NCBI and Uniprot Product Information
Uniprot Description
Component of the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Recruits the soluble ubiquitin-conjugating enzyme UBC7 to the cytoplasmic face of the endoplasmic reticulum membrane where it functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Targets the E2 conjugating enzyme UBC7 to the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains, and to the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M) ().
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Product Notes
The CUE1 cue1 (Catalog #AAA1386034) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-206. The amino acid sequence is listed below: MDNSTIVFIA VLGVAFIFLR WLIAPIPPQL PNELNEALAN SVNNSNRPNN SNNSNSATNS NANRRGRREP SDDMIEVVQT IAPQLTRGQI RMDLERSGSV EVTMERYMET GSLPFPPGES AATQSYQSDI SEHSQATKKE PENLIDKYDL KSKIKGDEGE GIENIDENKW GSSKEERSSL LNKKREEMIL QARKRLASQL QNEVAL. It is sometimes possible for the material contained within the vial of "Coupling of ubiquitin conjugation to ER degradation protein 1 (CUE1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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