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Mouse Catenin alpha-1 ELISA Kit | CTNNA1 elisa kit

Mouse Catenin alpha-1 (CTNNA1) ELISA Kit

Gene Names
Ctnna1; Catna1; AA517462; AI988031; 2010010M04Rik
Reactivity
Mouse
Synonyms
Catenin alpha-1; Mouse Catenin alpha-1 (CTNNA1) ELISA Kit; CTNNA1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse CTNNA1. No significant cross-reactivity or interference between Mouse CTNNA1 and analogues was observed.
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for CTNNA1 elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate CTNNA1 in samples. An antibody specific for CTNNA1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCTNNA1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CTNNA1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CTNNA1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
100,106 Da
NCBI Official Full Name
catenin alpha-1
NCBI Official Synonym Full Names
catenin (cadherin associated protein), alpha 1
NCBI Official Symbol
Ctnna1
NCBI Official Synonym Symbols
Catna1; AA517462; AI988031; 2010010M04Rik
NCBI Protein Information
catenin alpha-1
UniProt Protein Name
Catenin alpha-1
Protein Family
UniProt Gene Name
Ctnna1
UniProt Synonym Gene Names
Catna1

Uniprot Description

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

Research Articles on CTNNA1

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Product Notes

The Mouse CTNNA1 ctnna1 (Catalog #AAA281885) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA281885 ELISA Kit recognizes Mouse CTNNA1. It is sometimes possible for the material contained within the vial of "Catenin alpha-1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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