RNase E specificity factor CsrD (csrD) Recombinant Protein | csrD recombinant protein
Recombinant Escherichia coli RNase E specificity factor CsrD (csrD), partial
NCBI and Uniprot Product Information
NCBI Description
In its c-di-GMP domains CsrD has HRSDF instead of GGDEF and ELM instead of EAL and does not appear to have either diguanylate cyclase or cyclic-di-GMP phosphodiesterase activities and the role of CsrD in csrB/C destabilization does not involve cyclic-di-GMP metabolism (Suzuki, 2006). [More information is available at EcoGene: EG10018]. CsrD controls the degradation of the small RNAs CsrB and CsrC, thereby regulating the activity of CsrA and affecting the expression of CsrA-regulated genes. [More information is available at EcoCyc: EG10018].
Uniprot Description
Serves as a specificity factor required for RNase E-mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di-GMP, despite its domain composition. Positively modulates motility gene expression, is also required for curli expression.
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Product Notes
The csrD csrd (Catalog #AAA7059448) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RNase E specificity factor CsrD (csrD), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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