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CREB-regulated transcription coactivator 2 (Crtc2) Recombinant Protein | Crtc2 recombinant protein

Recombinant Rat CREB-regulated transcription coactivator 2 (Crtc2)

Gene Names
Crtc2; Torc2; RGD1308903
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
CREB-regulated transcription coactivator 2 (Crtc2); Recombinant Rat CREB-regulated transcription coactivator 2 (Crtc2); Crtc2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-691, full length protein
Sequence
ATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYPRHIDSSPYSPAYLSPPPESGWRRMMPWGNLPAEKGQLFRLPSALNRTSSDSALHTSVMNPNPQDTYPGPTPPSVLPSRRGGFLDGEMDAKVPAIEENLVDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMSTGGSLPDLTNLHFPPPLPTPLDPEETVYPSLSGGNSTTNLTHTMTHLGISGGLGLGPSYDVPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLAHHALPTTSLGHPSLSAPALSSSSSSSSTSSPVLSAPPYPASTPGASPRHRRVPLSPLSLPAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLPTDQRLPPYPYSPPSLVIPSHPPTPKSLQQLPSQACLVQPSGGQPPGRQPHYGTLYPPGSSGHGQQPYHRPINDFSLGNLEQFNMESPSTSLVLDPPAFSEGPGFLGSEGSVSGPQDSHVLNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSASGLELGLGLEDELRMEPLGLEGLTMLSDPCALLPDPAVEDSFRSDRLQ
Sequence Length
690
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
73,146 Da
NCBI Official Full Name
CREB-regulated transcription coactivator 2
NCBI Official Synonym Full Names
CREB regulated transcription coactivator 2
NCBI Official Symbol
Crtc2
NCBI Official Synonym Symbols
Torc2; RGD1308903
NCBI Protein Information
CREB-regulated transcription coactivator 2
UniProt Protein Name
CREB-regulated transcription coactivator 2
UniProt Gene Name
Crtc2
UniProt Synonym Gene Names
Torc2; TORC-2; Transducer of CREB protein 2

Uniprot Description

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells ().

Research Articles on Crtc2

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Product Notes

The Crtc2 crtc2 (Catalog #AAA1361347) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-691, full length protein. The amino acid sequence is listed below: ATSGANGPGS ATASASNPRK FSEKIALQKQ RQAEETAAFE EVMMDIGSTR LQAQKLRLAY TRSSHYGGSL PNVNQIGCGL AEFQSPLHSP LDSSRSTRHH GLVERVQRDP RRMVSPLRRY PRHIDSSPYS PAYLSPPPES GWRRMMPWGN LPAEKGQLFR LPSALNRTSS DSALHTSVMN PNPQDTYPGP TPPSVLPSRR GGFLDGEMDA KVPAIEENLV DDKHLLKPWD AKKLSSSSSR PRSCEVPGIN IFPSPDQPAN VPVLPPAMST GGSLPDLTNL HFPPPLPTPL DPEETVYPSL SGGNSTTNLT HTMTHLGISG GLGLGPSYDV PGLHSPLSHP SLQSSLSNPN LQASLSSPQP QLQGSHSHPS LPASSLAHHA LPTTSLGHPS LSAPALSSSS SSSSTSSPVL SAPPYPASTP GASPRHRRVP LSPLSLPAGP ADARRSQQQL PKQFSPTMSP TLSSITQGVP LDTSKLPTDQ RLPPYPYSPP SLVIPSHPPT PKSLQQLPSQ ACLVQPSGGQ PPGRQPHYGT LYPPGSSGHG QQPYHRPIND FSLGNLEQFN MESPSTSLVL DPPAFSEGPG FLGSEGSVSG PQDSHVLNHQ NLTHCSRHGS GPNIILTGDS SPGFSKEIAA ALAGVPGFEV SASGLELGLG LEDELRMEPL GLEGLTMLSD PCALLPDPAV EDSFRSDRLQ. It is sometimes possible for the material contained within the vial of "CREB-regulated transcription coactivator 2 (Crtc2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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