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SDS-PAGE

CREG / CREG1 recombinant protein

Recombinant Mouse CREG / CREG1 Protein (His tag)

Gene Names
Creg1; Creg; AA755314
Purity
> 95 % as determined by SDS-PAGE
Synonyms
CREG / CREG1; Recombinant Mouse CREG / CREG1 Protein (His tag); CREG; Creg1; CREG / CREG1 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
220
Application Notes
The recombinant mouse CREG comprises 200 amino acids and has a predicted molecular mass of 22.9 kDa. The apparent molecular mass of the protein is approximately 28-32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Arg 32
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for CREG / CREG1 recombinant protein
Background: CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.

Description: A DNA sequence encoding the mouse CREG (O88668) (Met1-Gln220) was expressed with a C-terminal polyhistidine tag.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,452 Da
NCBI Official Full Name
protein CREG1
NCBI Official Synonym Full Names
cellular repressor of E1A-stimulated genes 1
NCBI Official Symbol
Creg1
NCBI Official Synonym Symbols
Creg; AA755314
NCBI Protein Information
protein CREG1
UniProt Protein Name
Protein CREG1
UniProt Gene Name
Creg1
UniProt Synonym Gene Names
Creg

Uniprot Description

CREG1: May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R. Belongs to the CREG family.

Protein type: Secreted; Secreted, signal peptide; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1|1 H2.3

Cellular Component: extracellular space; transcription factor complex

Molecular Function: transcription factor binding

Biological Process: regulation of transcription, DNA-dependent

Research Articles on CREG / CREG1

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Product Notes

The CREG / CREG1 creg1 (Catalog #AAA2546679) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse CREG comprises 200 amino acids and has a predicted molecular mass of 22.9 kDa. The apparent molecular mass of the protein is approximately 28-32 kDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the CREG / CREG1 creg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CREG / CREG1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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