cAMP-responsive element-binding protein-like 2 (Crebl2) Recombinant Protein | Crebl2 recombinant protein
Recombinant Mouse cAMP-responsive element-binding protein-like 2 (Crebl2)
Gene Names
Crebl2; AI046348; B230205M03
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
cAMP-responsive element-binding protein-like 2 (Crebl2); Recombinant Mouse cAMP-responsive element-binding protein-like 2 (Crebl2); Crebl2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-123, full length protein
Sequence
MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIRALLTGEEQSKPQQNSSRHPKAGKTDANTNSLVGN
Sequence Length
123
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Crebl2 recombinant protein
cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14,002 Da
NCBI Official Full Name
cAMP-responsive element-binding protein-like 2
NCBI Official Synonym Full Names
cAMP responsive element binding protein-like 2
NCBI Official Symbol
Crebl2
NCBI Official Synonym Symbols
AI046348; B230205M03
NCBI Protein Information
cAMP-responsive element-binding protein-like 2
UniProt Protein Name
cAMP-responsive element-binding protein-like 2
Protein Family
UniProt Gene Name
Crebl2
Uniprot Description
Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle.
Research Articles on Crebl2
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Product Notes
The Crebl2 crebl2 (Catalog #AAA1438075) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-123, full length protein. The amino acid sequence is listed below: MDDSKVVGGK VKKPGKRGRK PAKIDLKAKL ERSRQSAREC RARKKLRYQY LEELVSSRER AICALREELE MYKQWCMAMD QGKIPSEIRA LLTGEEQSKP QQNSSRHPKA GKTDANTNSL VGN. It is sometimes possible for the material contained within the vial of "cAMP-responsive element-binding protein-like 2 (Crebl2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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