Cyclic AMP-responsive element-binding protein 3-like protein 4 (Creb3l4) Recombinant Protein | Creb3l4 recombinant protein
Recombinant Mouse Cyclic AMP-responsive element-binding protein 3-like protein 4 (Creb3l4), partial
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a CREB (cyclic AMP-responsive element-binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein may play a role in adiposity and male germ cell development. Homozygous knockout mice for this gene show increased adipogenesis, elevated testicular germ cell apoptosis and defects in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Uniprot Description
Transcriptional activator that may play a role in the unfolded protein response of the testis. Proposed to be involved in spermiogenesis. May be involved in regulating the maturation of sperm head nuclei. Alternatively proposed to be a paternally delivered transcription factor that may function in early zygotic gene activation. Increases the binding of CREM isoform Tau with CRE. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE but not through UPRE and may recruit HIRA to CRE to regulate histone exchange.
Research Articles on Creb3l4
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Product Notes
The Creb3l4 creb3l4 (Catalog #AAA1384322) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-271. The amino acid sequence is listed below: MELGCPELLE PPEDIFSTGS FLELGFNGPA SKVPVTRGLQ KSEPDDFLNL FIDPNMIHCS ETSPGRDSGV SEDPGSPAQQ ASSSPALYEV VYDSGTLQGT QREAGPTFGL ISIQIDQWTP ALMVPDACTV SGLPSDSHRH ILPRVSTRAP APPAAMPSCQ HHLFLTDEEK QLLAQEGITL PSHLPLTKAE ERILKKIRRK IRNKQSAQDS RRRKKEYLDG LESRVAACSE QNQKLQRKVQ ELERQNIFLM EQVRQLQKLT AQTSSRAAQT S. It is sometimes possible for the material contained within the vial of "Cyclic AMP-responsive element-binding protein 3-like protein 4 (Creb3l4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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