CAMP Responsive Element Binding Protein 3-Like 2 Recombinant Protein | CREB3L2 recombinant protein
Recombinant Human CAMP Responsive Element Binding Protein 3-Like 2
Gene Names
CREB3L2; BBF2H7
Purity
Greater than 85% as determined by SDS-PAGE.
Synonyms
CAMP Responsive Element Binding Protein 3-Like 2; Recombinant Human CAMP Responsive Element Binding Protein 3-Like 2; CREB3L2 Human; CAMP Responsive Element Binding Protein 3-Like 2 Human Recombinant; BBF2H7; CAMP-Responsive Element-Binding Protein 3-Like Protein 2; BBF2 Human Homolog On Chromosome 7; Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 2; Basic Transcription Factor 2; B-ZIB Transcription Factor; FUS/BBF2H7 Protein; TCAG_1951439; Cyclic AMP-responsive element-binding protein 3-like protein 2; cAMP-responsive element-binding protein 3-like protein 2; CREB3L2 recombinant protein
Host
E Coli
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Form/Format
CREB3L2 protein solution (0.25mg/ml) containing PBS (pH 7.4), 30% glycerol and 1mM DTT.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEVLESG EQGVLQWDRK LSELSEPGDG EALMYHTHFS ELLDEFSQNVLGQLLNDPFL SEKSVSMEVE PSPTSPAPLI QAEHSYSLCE EPRAQSPFTH ITSDSFNDDE VESEKWYLSTDFPSTSIKTE PITDEPPPGL VPSVTLTITA ISTPLEKEEPPLEMNTGVDS SCQTIIPKIK LEPHEVDQFL NFSPKEAPVD HLHLPPTPPSSHGSDSEGSL SPNPRLHPFS LPQTHSPSRA APRAPSALSS SPLLTAPHKL QGSGPLVLTE EEKRTLIAEGYPIPTKLPLS KSEEKALKKI RRKIKNKISA QESRRKKKEY MDSLEKKVES CSTENLELRKKVEVLENTNR TLLQQLQKLQ TLVMGKVSRT CKLAGTQTGT C
Sequence Length
248
Related Product Information for CREB3L2 recombinant protein
Introduction: CAMP Responsive Element Binding Protein 3-Like 2, also known as CREB3L2 belongs to the oasis bZIP transcription factor family. Members of this family are able to dimerize however from homodimers only. CREB3L2 is a transcriptional activator. Translocations between CREB3L2 on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. One disease which is associated with CREB3L2 is myxofibrosarcoma.
Description: CREB3L2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 401 amino acids (1-378 a.a) and having a molecular mass of 44kDa. CREB3L2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Description: CREB3L2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 401 amino acids (1-378 a.a) and having a molecular mass of 44kDa. CREB3L2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for CREB3L2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,722 Da
NCBI Official Full Name
cyclic AMP-responsive element-binding protein 3-like protein 2 isoform 2
NCBI Official Synonym Full Names
cAMP responsive element binding protein 3-like 2
NCBI Official Symbol
CREB3L2
NCBI Official Synonym Symbols
BBF2H7
NCBI Protein Information
cyclic AMP-responsive element-binding protein 3-like protein 2
UniProt Protein Name
Cyclic AMP-responsive element-binding protein 3-like protein 2
Protein Family
UniProt Gene Name
CREB3L2
UniProt Synonym Gene Names
BBF2H7; cAMP-responsive element-binding protein 3-like protein 2
UniProt Entry Name
CR3L2_HUMAN
Uniprot Description
CREB3L2: Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage. A chromosomal aberration involving CREB3L2 is found in low grade fibromyxoid sarcoma (LGFMS). Translocation t(7;16)(q33;p11) with FUS. Belongs to the bZIP family. ATF subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 7q34
Cellular Component: endoplasmic reticulum; nucleoplasm; nucleus
Biological Process: cartilage development; chondrocyte differentiation; positive regulation of transcription, DNA-dependent
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Product Notes
The CREB3L2 creb3l2 (Catalog #AAA140873) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMEV LESG EQGVLQWDRK LSELSEPGDG EALMYHTHFS ELLDEFSQNV LGQLLNDPFL SEKSVSMEVE PSPTSPAPLI QAEHSYSLCE EPRAQSPFTH ITSDSFNDDE VESEKWYLST DFPSTSIKTE PITDEPPPGL VPSVTLTITA ISTPLEKEEP PLEMNTGVDS SCQTIIPKIK LEPHEVDQFL NFSPKEAPVD HLHLPPTPPS SHGSDSEGSL SPNPRLHPFS LPQTHSPSRA APRAPSALSS SPLLTAPHKL QGSGPLVLTE EEKRTLIAEG YPIPTKLPLS KSEEKALKKI RRKIKNKISA QESRRKKKEY MDSLEKKVES CSTENLELRK KVEVLENTNR TLLQQLQKLQ TLVMGKVSRT CKLAGTQTGT C. It is sometimes possible for the material contained within the vial of "CAMP Responsive Element Binding Protein 3-Like 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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