Testing Data
(Peptide-+)
anti-Human, Mouse Cytochrome P450 2R1 Antibody | anti-CP2R1 antibody
Cytochrome P450 2R1 Antibody
Reactivity
Human, Mouse
Applications
Western Blot, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Cytochrome P450 2R1; Cytochrome P450 2R1 Antibody; EC 1.14.14.-; Vitamin D 25-hydroxylase; CYP2R1; anti-CP2R1 antibody
Reactivity
Human, Mouse
Specificity
Cytochrome P450 2R1 antibody detects endogenous levels of total Cytochrome P450 2R1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
501
Applicable Applications for anti-CP2R1 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:40000
IF: 1:100~1:500
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human Cytochrome P450 2R1.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(Peptide-+)
Testing Data
(Peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Cytochrome P450 2R1 antibody. Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2R1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Cytochrome P450 2R1 antibody. Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2R1 antibody.)
Product Categories/Family for anti-CP2R1 antibody
References
Cheng J.B., J. Biol. Chem. 278:38084-38093(2003). Shinkyo R., Biochem. Biophys. Res. Commun. 324:451-457(2004). Cheng J.B., Proc. Natl. Acad. Sci. U.S.A. 101:7711-7715(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,359 Da
NCBI Official Full Name
vitamin D 25-hydroxylase
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily R member 1
NCBI Official Symbol
CYP2R1
NCBI Protein Information
vitamin D 25-hydroxylase
UniProt Protein Name
Vitamin D 25-hydroxylase
UniProt Gene Name
CYP2R1
NCBI Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]
Uniprot Description
Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D2 and D3.
Research Articles on CP2R1
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Product Notes
The CP2R1 cyp2r1 (Catalog #AAA857980) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Cytochrome P450 2R1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Cytochrome P450 2R1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000. Researchers should empirically determine the suitability of the CP2R1 cyp2r1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytochrome P450 2R1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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