KLF13 blocking peptide
KLF13 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]
Uniprot Description
KLF13: Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells. Belongs to the Sp1 C2H2-type zinc-finger protein family.
Protein type: DNA-binding; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 15q12
Cellular Component: nucleus
Molecular Function: metal ion binding; protein binding
Biological Process: negative regulation of cell proliferation; negative regulation of erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Disease: Chromosome 15q13.3 Deletion Syndrome
Research Articles on KLF13
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Product Notes
The KLF13 klf13 (Catalog #AAA427607) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The KLF13 Immunizing Peptide reacts with Human, Mouse, Pig, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-TLPRVEER RDGKDS. It is sometimes possible for the material contained within the vial of "KLF13, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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