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MAP3K6 blocking peptide

MAP3K6 Immunizing Peptide

Gene Names
MAP3K6; ASK2; MEKK6; MAPKKK6
Reactivity
Human, Mouse, Rat, Dog, Cow
Synonyms
MAP3K6; MAP3K6 Immunizing Peptide; mitogen-activated protein kinase kinase kinase 6; ASK2; MAPKKK6; MGC125653; MGC20114; OTTHUMP00000005063; apoptosis signal-regulating kinase 2; MAP3K6 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat, Dog, Cow
Form/Format
100ug of dried peptide
Sequence
C-RAILAQRAGSTP
Sequence Length
1288
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
141,648 Da
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase 6 isoform 1
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 6
NCBI Official Symbol
MAP3K6
NCBI Official Synonym Symbols
ASK2; MEKK6; MAPKKK6
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 6
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 6
UniProt Gene Name
MAP3K6
UniProt Synonym Gene Names
ASK2; MAPKKK6; MEKK6
UniProt Entry Name
M3K6_HUMAN

NCBI Description

This gene encodes a serine/threonine protein kinase that forms a component of protein kinase-mediated signal transduction cascades. The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Uniprot Description

MEKK6: a member of the STE11 protein kinase family. Activates JNK, but not ERK or p38. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Protein type: Protein kinase, STE; EC 2.7.11.25; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; STE group; STE11 family

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: intracellular

Molecular Function: ATP binding; magnesium ion binding; MAP kinase kinase kinase activity

Biological Process: activation of JNK activity; activation of MAPKK activity; protein amino acid phosphorylation; signal transduction

Research Articles on MAP3K6

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Product Notes

The MAP3K6 map3k6 (Catalog #AAA426605) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The MAP3K6 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-RAILAQRA GSTP. It is sometimes possible for the material contained within the vial of "MAP3K6, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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