Testing Data
(Immobilized Human ACE-2-Fc at 10ug/ml (100ul/well) can bind 2019-nCoV S1 Protein-Fc*.*: Biotinylated by NHS-biotin prior to testing. The ED50 of 2019-nCoV S1 Protein-Fc* is 0.85 ug/ml.)
COVID 19 Spike S1 COVID 19 Recombinant Protein | COVID-19 recombinant protein
Recombinant 2019-nCoV S1 Protein (C-Fc) (Mammalian expression)
Purity
>90% as determined by reducing SDS-PAGE.
Synonyms
COVID 19 Spike S1 COVID 19; Recombinant 2019-nCoV S1 Protein (C-Fc) (Mammalian expression); 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike S1; COVID-19 recombinant protein
Host
Mammalian cells
Purity/Purification
>90% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 um filtered solution of PBS, 10% Glycerol, pH7.4.
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Testing Data
(Immobilized Human ACE-2-Fc at 10ug/ml (100ul/well) can bind 2019-nCoV S1 Protein-Fc*.*: Biotinylated by NHS-biotin prior to testing. The ED50 of 2019-nCoV S1 Protein-Fc* is 0.85 ug/ml.)
Testing Data
(Immobilized Human ACE-2-Fc at 10ug/ml (100ul/well) can bind 2019-nCoV S1 Protein-Fc*.*: Biotinylated by NHS-biotin prior to testing. The ED50 of 2019-nCoV S1 Protein-Fc* is 0.85 ug/ml.)
Related Product Information for COVID-19 recombinant protein
2019-nCoV Recombinant Protein Antigen
Recombinant 2019-nCoV S1 Protein is produced by our Mammalian expression system and the target gene encoding Gln14-Arg685 is expressed with a Fc tag at the C-terminus.
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors.
Recombinant 2019-nCoV S1 Protein is produced by our Mammalian expression system and the target gene encoding Gln14-Arg685 is expressed with a Fc tag at the C-terminus.
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors.
NCBI and Uniprot Product Information
Molecular Weight
MW: 102.2kDa
AP MW: 130-140kDa, reducing conditions
AP MW: 130-140kDa, reducing conditions
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Product Notes
The COVID-19 (Catalog #AAA8574931) is a Recombinant Protein produced from Mammalian cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "COVID 19 Spike S1 COVID 19, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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