COVID 19 NSP7 Protein Coronavirus Recombinant Protein | COVID-19 recombinant protein
Recombinant 2019-nCoV NSP7 Protein (His Tag)
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
COVID 19 NSP7 Protein Coronavirus; Recombinant 2019-nCoV NSP7 Protein (His Tag); 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; SARS-CoV 2 nsp7; COVID-19 recombinant protein
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 um Filtered Solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5.
Concentration
1.74mg/ml (varies by lot)
Sequence Positions
Ser1-Gln83
Sequence Length
83
Species
Virus
Endotoxin
< 1.0 EU per ug as determined by the LAL method.
Fusion Tag
C-6His
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Ships on dry ice. Store at <-20°C.
Avoid repeated freeze thaw cycles.
Avoid repeated freeze thaw cycles.
Related Product Information for COVID-19 recombinant protein
Protein Construction: Recombinant 2019-nCoV NSP7 is produced by our E.coli expression system and the target gene encoding Ser1-Gln83 is expressed with a 6His tag at the C-terminus.
Background: The ~30kb positive-stranded RNA genome of coronaviruses encodes a replication/transcription machinery that is unusually complex and composed of 16 nonstructural proteins (nsps). The four proteins nsp7 to nsp10, which are conserved among all CoVs but have no functional homologs outside of the Coronaviridae, are translated as part of the viral polyproteins pp1a and pp1ab, and the mature proteins are released by the action of the SARS-CoV protease nsp5. Hexadecamer of nsp7 and nsp8 may possess dsRNA-binding activity. SARS-CoV 2 nonstructural protein 7 (nsp7) is of interest for its potential roles in the transcription and replication of the positive-stranded viral RNA genome.
Background: The ~30kb positive-stranded RNA genome of coronaviruses encodes a replication/transcription machinery that is unusually complex and composed of 16 nonstructural proteins (nsps). The four proteins nsp7 to nsp10, which are conserved among all CoVs but have no functional homologs outside of the Coronaviridae, are translated as part of the viral polyproteins pp1a and pp1ab, and the mature proteins are released by the action of the SARS-CoV protease nsp5. Hexadecamer of nsp7 and nsp8 may possess dsRNA-binding activity. SARS-CoV 2 nonstructural protein 7 (nsp7) is of interest for its potential roles in the transcription and replication of the positive-stranded viral RNA genome.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 12.3 kDa
Actual Protein Molecular Mass: 12 kDa
Actual Protein Molecular Mass: 12 kDa
NCBI Official Full Name
nsp7
