Human COVID 19 Nucleocapsid (NP) IgG Coronavirus ELISA Kit | COVID-19 elisa kit
Human COVID-19 Nucleocapsid (NP) IgG Antibody ELISA Kit
Principle of the Assay: The human COVID-19 IgG antibody ELISA is made from the 2019-nCoV N protein coated microtiter plate, mouse-anti-human IgG-HRP and other reagents. It applies the indirect ELISA principle to test the antibodies against 2019-nCoV in human serum. In the test, the coated N protein combine with COVID-19 IgG antibody in serum, then add IgG-HRP to specifically bind with complex of antibody-antigens on the microplate. With the TMB substrate, it will generate an amount of color. The depth of color is relative with the content of the COVID-19 IgG antibody in the serum sample.
Background/Introduction: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a test tool.
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Product Notes
The Human COVID-19 (Catalog #AAA3809906) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3809906 ELISA Kit recognizes Human COVID-19. It is sometimes possible for the material contained within the vial of "COVID 19 Nucleocapsid (NP) IgG Coronavirus, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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