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COVID 19 Nucleoprotein IgG Coronavirus ELISA Kit | COVID-19 elisa kit

COVID-19 Nucleoprotein Human IgG ELISA Assay

Synonyms
COVID 19 Nucleoprotein IgG Coronavirus; COVID-19 Nucleoprotein Human IgG ELISA Assay; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Nucleocapsid; Nucleoprotein (NP); COVID-19 elisa kit
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For Research Use Only!
Related Product Information for COVID-19 elisa kit
Principle of the Assay: Microtitration wells coated with alternating strips of recombinant COVID-19 Nucleoprotein (N) viral antigen and negative control antigen are exposed to test specimens, which may contain human IgG antibodies directed against COVID-19 N protein. After an incubation period, unbound antibodies in the test sample are washed away. Bound COVID-19 N protein IgG antibodies are then incubated with an anti-human/mouse IgG peroxidase conjugate. Following a second wash cycle, the bound peroxidase conjugate is detected by the addition of ABTS peroxidase substrate. The assay is measured spectrophotometrically to indicate the abundance of COVID-19 N protein human IgG antibodies present in a sample.

Background/Introduction: Outbreaks with a novel coronavirus disease COVID-19 is caused by the SARS-CoV-2 virus. The virus has shown to be very contagious and has caused a worldwide pandemic in the Spring of 2020. The SARS-CoV-2 virus is a single strand RNA virus with glycoprotein spikes on its surface. The spike protein (S) contains the receptor-binding domain (RBD) which has affinity to the angiotensin-converting enzyme 2 (ACE2). The interaction between RBD and ACE2 mediates the fusion of the viral and cellular membranes starting the infection process. The S protein has two subunits, S1 and S2. S1 contains the RBD region and the S2 is associated with the membrane of the virus. The nucleoprotein (N) is an abundant protein associated with virus structure and replication. Human ELISA assays have been developed using the S proteins and nucleoprotein of SARS-CoV-2 to detect antibodies to SARS-CoV-2.

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Product Notes

The COVID-19 (Catalog #AAA412773) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "COVID 19 Nucleoprotein IgG Coronavirus, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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