Test Data
(Bioactivity test of Recombinant 2019-nCoV 3C-like Proteinase (N-6His) (CAT# MBS8574760) measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic) (CAT# MBS8574873).The specific activity is >13000pmol/min/mg.)
COVID 19 3C-like Proteinase Coronavirus Active Protein | COVID-19 active protein
Recombinant 2019-nCoV 3C-like Proteinase (N-6His) (CR76)
Purity
> = 95% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Synonyms
COVID 19 3C-like Proteinase Coronavirus; Recombinant 2019-nCoV 3C-like Proteinase (N-6His) (CR76); 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; COVID-19 active protein
Specificity
2019-Ncov
Purity/Purification
> = 95% as determined by reducing SDS-PAGE. Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Form/Format
Supplied as a 0.2 um filtered solution of PBS, 1mM EDTA, 10% Glycerol, pH 7.4.
Isoelectric point
6.2
Reaction
Dabcyl-KTSAVLQSGFRKME-Edans 3CLP Dabcyl-KTSAVLQ + SGFRKME-Edans
Definition of activity
One unit is 1pmol sgfrkme-edans was catalyzed per minute at pH 7.0 and temperature 37°C
Activity
>= 13000 u/mg. Disclaimer: The activity data is for reference only. Not guaranteed. Each researcher should verify the enzyme activity in their own model system.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Ships on dry ice. Store at < -20°C, stable for 6 months after receipt.
Test Data
(Bioactivity test of Recombinant 2019-nCoV 3C-like Proteinase (N-6His) (CAT# MBS8574760) measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic) (CAT# MBS8574873).The specific activity is >13000pmol/min/mg.)
Test Data
(Bioactivity test of Recombinant 2019-nCoV 3C-like Proteinase (N-6His) (CAT# MBS8574760) measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic) (CAT# MBS8574873).The specific activity is >13000pmol/min/mg.)
Test Data
(Measurements of kinetic parameters of Recombinant 2019-nCoV 3C-like Proteinase (CAT# MBS8574760) (For reference only).)
Test Data
(Measurements of kinetic parameters of Recombinant 2019-nCoV 3C-like Proteinase (CAT# MBS8574760) (For reference only).)
Related Product Information for COVID-19 active protein
2019-nCoV Recombinant Proteinase
Recombinant 2019-nCoV 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser1-Gln306 is expressed with a 6His tag at the N-terminus.
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
Recombinant 2019-nCoV 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser1-Gln306 is expressed with a 6His tag at the N-terminus.
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.
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Product Notes
The COVID-19 (Catalog #AAA8574760) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "COVID 19 3C-like Proteinase Coronavirus, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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