Probable serine/threonine-protein kinase COQ8, mitochondrial (COQ8) Recombinant Protein | COQ8 recombinant protein

Recombinant Saccharomyces cerevisiae Probable serine/threonine-protein kinase COQ8, mitochondrial (COQ8)

Gene Names

COQ8; ABC1

Purity

Greater or equal to 85% purity as determined by SDS-PAGE.

Synonyms

Probable serine/threonine-protein kinase COQ8; mitochondrial (COQ8); Recombinant Saccharomyces cerevisiae Probable serine/threonine-protein kinase COQ8; COQ8 recombinant protein

Ordering
Cat. Num. AAA1023781 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE.

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Sequence Positions

30-501, full length protein

Sequence

SSVSSISLSKKYTTKSAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV

Sequence Length

472

Species

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #

6321319

NCBI GeneID

852758

NCBI Accession #

NP_011396.1

NCBI GenBank Nucleotide #

NM_001180984.1

UniProt Accession #

P27697; D6VU29

Molecular Weight

56,742 Da

NCBI Official Full Name

protein kinase COQ8

NCBI Official Symbol

COQ8

NCBI Official Synonym Symbols

ABC1

NCBI Protein Information

protein kinase COQ8

UniProt Protein Name

Atypical kinase COQ8, mitochondrial

Protein Family

Atypical kinase

UniProt Gene Name

COQ8

UniProt Synonym Gene Names

ABC1

Uniprot Description

Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Affects the molecular organization and function of COQ3, possibly through kinase activity towards COQ3, COQ5 and/or COQ7 (PubMed:11279158, PubMed:15063807, PubMed:1648478, PubMed:18801050, PubMed:19002377, PubMed:21296186, PubMed:9210471, PubMed:9266513, PubMed:25498144). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates ().

Research Articles on COQ8

1. ADCK3/COQ8 localises to mitochondrial cristae and is targeted to this organelle via the presence of an N-terminal localisation signal

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Product Notes

The COQ8 coq8 (Catalog #AAA1023781) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 30-501, full length protein. The amino acid sequence is listed below: SSVSSISLSK KYTTKSAKEG EENVERKHEE EKKDTLKSSS VPTSRISRLF HYGSLAAGVG MNAAAKGISE VAKGNSPTWK SLILSDSNID RITNKFSKMR GVALKIGQLL SFQDEKVLPK ELYEILSRVQ NSANHMPQRQ LEKVMAKELG ANWKTKFSKF DKIPMAAASI GQVHAAELPS GQRVVVKIQY PGVKESIDSD LNSLLMLLTA SSLLPKGLFL DKTIANARTE LKWECDYNRE ARALQKFEAL LKDDPAFEVP HVFPEYTTDN IITMTRMEGT EIMKLPKASQ ETKNFISENI MRLCLEEIAT FKYMQTDPNW ANFLYNGRTK KIELLDFGAS RPFAEDFILK YRKLLTYATL RDRKGAYEMS VQLGYLTGLE SQSMKDAHVD SVLTLGEPFR GDVDKSFDFK DQTVSDRIRG NIGLMLNERL CPPPEETYSL HRKFSGIFLL CARMGASVHC AKLFKEIFAY KV. It is sometimes possible for the material contained within the vial of "Probable serine/threonine-protein kinase COQ8, mitochondrial (COQ8), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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