Forskolin Biochemical
Forskolin (7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy- labd-14-ene-11-one, Colforsin)
Purity
Highly Purified99% TLC (NP, DCM, methanol 95:5)
99% TLC (RP C18, methanol, H2O 9:1)
Detection, spray with H2SO4 and heat
Synonyms
Forskolin; Forskolin (7b-Acetoxy-8; 13-epoxy-1a; 6b; 9a-trihydroxy- labd-14-ene-11-one; Colforsin); Forskolin biochemical
Host
Coleus forskohlii
Purity/Purification
Highly Purified
99% TLC (NP, DCM, methanol 95:5)
99% TLC (RP C18, methanol, H2O 9:1)
Detection, spray with H2SO4 and heat
99% TLC (NP, DCM, methanol 95:5)
99% TLC (RP C18, methanol, H2O 9:1)
Detection, spray with H2SO4 and heat
Form/Format
Supplied as a white to off-white crystalline powder.
CAS Number
66575-29-9
Molecular Formula
C22H34O7
Specific Rotation
-26.19º
Melting Point
228-230 degree C
Solubility
Solubility (10mg/ml Ethyl acetate): Clear, colorless solution. Soluble in ethanol, chloroform and DMSO.
Note: Various solvents including ethanol, inhibited the forskolin activation of adenylate cyclase. Recommended to use DMSO at concentrations of < 5%.
Note: Various solvents including ethanol, inhibited the forskolin activation of adenylate cyclase. Recommended to use DMSO at concentrations of < 5%.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Stability: Light sensitive
Stability: Light sensitive
Related Product Information for Forskolin biochemical
Forskolin is a powerful activator of adenyklate cyclase, resulting in an increase of intracellular cAMP concentration.1,2 Activates adenylate cyclase leading to an increase in the intracellular concentration of cAMP. Widely used tool for the investigation of the role of cAMP as a second messenger with a broad range of potential therapeutic applications. Inotropic agent and vasodilator. Induces platelet aggregation. Inhibits ion channels by a mechanism that does not involve cAMP. Non-competitive inhibitor of nicotinic acetylcholine receptors.
Product Categories/Family for Forskolin biochemical
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Product Notes
The Forskolin (Catalog #AAA6098026) is a Biochemical produced from Coleus forskohlii and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Forskolin, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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