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CNOT3 recombinant protein

Recombinant Human CNOT3

Gene Names
CNOT3; NOT3; LENG2; NOT3H
Applications
Western Blot, ELISA
Purity
Greater than 85% by SDS-PAGE gel analyses
Synonyms
CNOT3; Recombinant Human CNOT3; CCR4 associated factor 3; KIAA0691; LENG2; NOT3; NOT3H; CNOT3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85% by SDS-PAGE gel analyses
Form/Format
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4
Sequence Positions
501-753
Applicable Applications for CNOT3 recombinant protein
Western Blot (WB), ELISA (EIA)
Species
Human
Tag
N-terminal His-IF2DI Tag
Reconstitution
Centrifuge the vial at 10,000rpm for 1 minute, reconstitute at 200ug/ml in sterile distilled water
Preparation and Storage
Store at -20 degree C for 12 months as lyophilized; 2-8 degree C for 1 month under sterile conditions after reconstitution

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
81,872 Da
NCBI Official Full Name
CCR4-NOT transcription complex subunit 3
NCBI Official Synonym Full Names
CCR4-NOT transcription complex, subunit 3
NCBI Official Symbol
CNOT3
NCBI Official Synonym Symbols
NOT3; LENG2; NOT3H
NCBI Protein Information
CCR4-NOT transcription complex subunit 3; CCR4-associated factor 3; leukocyte receptor cluster member 2; NOT3 (negative regulator of transcription 3, yeast) homolog
UniProt Protein Name
CCR4-NOT transcription complex subunit 3
UniProt Gene Name
CNOT3
UniProt Synonym Gene Names
KIAA0691; LENG2; NOT3
UniProt Entry Name
CNOT3_HUMAN

Uniprot Description

NOT3: The CCR4-NOT complex functions as general transcription regulation complex. Belongs to the CNOT2/3/5 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.4

Cellular Component: nucleus; cytosol; CCR4-NOT complex

Molecular Function: protein binding

Biological Process: regulation of translation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA-mediated gene silencing; gene expression; mRNA catabolic process, deadenylation-dependent decay; trophectodermal cell differentiation

Research Articles on CNOT3

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Product Notes

The CNOT3 cnot3 (Catalog #AAA7614776) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 501-753. AAA Biotech's CNOT3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Researchers should empirically determine the suitability of the CNOT3 cnot3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNOT3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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