Nuclear envelope phosphatase-regulatory subunit 1 (CNEP1R1) Recombinant Protein | CNEP1R1 recombinant protein

Recombinant Human Nuclear envelope phosphatase-regulatory subunit 1 (CNEP1R1), partial

• Gene Names: CNEP1R1; NEP1R1; TMP125; NEP1-R1; TMEM188; C16orf69
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Nuclear envelope phosphatase-regulatory subunit 1 (CNEP1R1); Recombinant Human Nuclear envelope phosphatase-regulatory subunit 1 (CNEP1R1); partial; CNEP1R1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 125

• Species: Homo sapiens (Human)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 529250119
• NCBI GeneID: 255919
• NCBI Accession #: NP_001268718.1
• NCBI GenBank Nucleotide #: NM_001281789.1
• UniProt Accession #: Q8N9A8; Q4G1A9; Q5H9V0; Q8NE06
• Molecular Weight: 5,618 Da
• NCBI Official Full Name: nuclear envelope phosphatase-regulatory subunit 1 isoform 2
• NCBI Official Synonym Full Names: CTD nuclear envelope phosphatase 1 regulatory subunit 1
• NCBI Official Symbol: CNEP1R1
• NCBI Official Synonym Symbols: NEP1R1; TMP125; NEP1-R1; TMEM188; C16orf69
• NCBI Protein Information: nuclear envelope phosphatase-regulatory subunit 1
• UniProt Protein Name: Nuclear envelope phosphatase-regulatory subunit 1
• Protein Family: Nuclear envelope phosphatase-regulatory
• UniProt Gene Name: CNEP1R1
• UniProt Synonym Gene Names: C16orf69; TMEM188; NEP1-R1

NCBI Description

This gene encodes a transmembrane protein that belongs to the Tmemb_18A family. A similar protein in yeast is a component of an endoplasmic reticulum-associated protein phosphatase complex and is thought to play a role in the synthesis of triacylglycerol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Description

Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.