Clathrin light chain A Recombinant Protein | Clta recombinant protein

Recombinant Mouse Clathrin light chain A

Cat. Num. AAA1060561

• Gene Names: Clta; Lca; AV026556
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Clathrin light chain A; Recombinant Mouse Clathrin light chain A; Clta recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-235aa; Full Length
• Sequence: MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGRATRRAAGGPDAVDGVMNGEYYQESNGPTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADLIGYVAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH
• Sequence Length: 235

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for Clta recombinant protein

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.

References

E3, a hematopoietic-specific transcript directly regulated by the retinoic acid receptor alpha.Scott L.M., Mueller L., Collins S.J. Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.Mol. Cell 50:919-930(2013)

NCBI and Uniprot Product Information

• NCBI GI #: 408360022
• NCBI GeneID: 12757
• UniProt Accession #: O08585
• Molecular Weight: 31.1 kDa
• NCBI Official Full Name: Clathrin light chain A
• NCBI Official Synonym Full Names: clathrin, light polypeptide (Lca)
• NCBI Official Symbol: Clta
• NCBI Official Synonym Symbols: Lca; AV026556
• NCBI Protein Information: clathrin light chain A
• UniProt Protein Name: Clathrin light chain A
• Protein Family: Clathrin
• UniProt Gene Name: Clta
• UniProt Synonym Gene Names: Lca
• UniProt Entry Name: CLCA_MOUSE

NCBI Description

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

CLTA: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Belongs to the clathrin light chain family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Vesicle

Cellular Component: clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin vesicle coat; clathrin-coated vesicle; coated pit; cytoplasmic membrane-bound vesicle; cytoplasmic vesicle; intracellular membrane-bound organelle; membrane

Molecular Function: clathrin heavy chain binding; peptide binding; structural molecule activity

Biological Process: intracellular protein transport; vesicle-mediated transport