Protein CLEC16A (CLEC16A) Recombinant Protein | CLEC16A recombinant protein

Recombinant Human Protein CLEC16A (CLEC16A) , partial

• Gene Names: CLEC16A; Gop-1; KIAA0350
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Protein CLEC16A (CLEC16A); Recombinant Human Protein CLEC16A (CLEC16A); partial; CLEC16A recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 140

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 343478149
• NCBI GeneID: 23274
• NCBI Accession #: NP_001230332.1
• NCBI GenBank Nucleotide #: NM_001243403.1
• UniProt Accession #: Q2KHT3; O15058; Q6ZTB2
• Molecular Weight: 14,283 Da
• NCBI Official Full Name: protein CLEC16A isoform 2
• NCBI Official Synonym Full Names: C-type lectin domain containing 16A
• NCBI Official Symbol: CLEC16A
• NCBI Official Synonym Symbols: Gop-1; KIAA0350
• NCBI Protein Information: protein CLEC16A
• UniProt Protein Name: Protein CLEC16A
• Protein Family: Protein
• UniProt Gene Name: CLEC16A

NCBI Description

This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Uniprot Description

Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PRKN. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.